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胆囊结石患者的血清脂质研究 被引量:6

Lipid metabolism studies in patients with gallstones
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摘要 本文对51例胆石病患者和19例非胆石病者,测定了20项与脂质代谢有关的指标。t检验提示:胆石组血apoB-100和血清胰岛素高于非胆石组(P<0.05),红细胞超氧化物歧化酶低于非胆石组(P<0.05)。对20项指标作逐步判别分析发现,apoA-1,HDL-Ch和LDL-Ch三项指标所构成的函数式对两类判别起重要作用(P<0.05),其中胆石组apoA-1和HDL-Ch高于非胆石组、LDL-Ch低于非胆石组。提示胆石病者存在脂质代谢异常。 To investigate the lipid metabolism in gallstone patients,20 variables havebeen studied such as % ideal body weight,superoxide dismutase(SOD)on red blood cells,SOD and lipid peroxde in serum, total serum cholesterol(Ch).HDL-Ch,LDL-Ch,VLDL-Ch,serum triglyceride(TG),HDL-TG,LDL-TG,VLDL一TG,serum bile acids(DCA,CDCA,UDCA,CA),serum insulin and serum apolipoprotein(apo A-1,apo B-100 ,apo A-1/apoB-100).t-test showed that apo B-100 and serum insulin were striking by higher and SODin RBC was lower in stone group than those in non-stone group.Apo A-1 and HDL-Chwere also higher and LDL-Ch was lower in stone group,albeit non-significantly so( P>0.05)in t-test,than those in non-stone's,but these three variables show remarkablly gooddiscriminating power in stepwise discriminating analysis of the 20 variables,which demon-strate that there are some difference between patients with and without gallstones in body-lipid metabolism.
出处 《中国病理生理杂志》 CAS CSCD 北大核心 1995年第2期170-173,共4页 Chinese Journal of Pathophysiology
关键词 胆结石 胆甾醇 脂蛋白类 胆汁酸和胆盐类 Cholelithiasis Cholesterol Lipoproteins Bile acids and salts
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