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腹腔镜胆囊切除术中肺功能变化的临床研究 被引量:5

CHANGES IN PULMONARY FUNCTION DURINGLAPAROSCOPIC CHOLECYSTETOMY
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摘要 本文观察了12例ASA1级胆囊结石病人腹腔镜胆囊切除术中的肺功能变化。年龄为40.7±9.4岁,体重61.4±9.4kg。Midazolam-Fentanyl-Isoflurane-Tracrium维持麻醉,控制呼吸,间歇正压通气。连续监测吸气气道峰压(PIP),动态肺应性(LC),PECO2,EKG,NIBP和SpO2。结果:体位改变对PIP和PECO2无明显影响(P>0.05),却使LC下降9.7%(P>0.05)。腹腔充气后30分钟PIP上升17%(P<0.05),LC与麻醉后和充气前相比分别下降25.8%和20.8%(P<0.01),PECO2增加19.1%(P<0.01);腹腔充气后60分钟,PIP和PECO2未继续增加,但LC继续下降,比麻醉后和充气前下降34.2%和27.1%(P<0.01)。本文显示腹腔镜胆囊切除术中肺顺应性显著下降,气道压明显升高,PECO2明显增加。 he measurement of pulmonary function in the operating room has recently becomeavaillable using corresponding equipment. The effects of abdomina insuffiation with CO2 andTredlenburg’s position on pulmonary function were sludied by using Datex Ultima to mea-sure pulmonary function alterations in patients undergoing laparoscopic cholecystectomy.12 ASA Ⅰ patients undergoing laparoscopic cholecystectomy were studied. After pre-medication with luminal and atropine, anesthesia was given with Madazolam-Fentanyl-lsoflurane-Tracurium. We used the Ultima side stream spirometer to measure peak inspira-tory pressure (PIP), Lung compliance (LC) and P(ET) CO2. We monitored EKG, NIBP andSpO2 with a device of Spacelabs. IPPV was initiated at a rate of respipatory 12/MIN andminute volume was adjusted to maintain a P(ET)CO2 of 35±2 mmHg. Values were recorded af-ter induction for 15 minutes, receiving Trendelenburg’s position for 10 minutes , before ab-dominal insuffiation with CO2 andafter insuffiation with CO2 for 30 and 60 minutes. Datawere analyzed with paired student’s t test with P<0. 05 consided significant.PIP and P(ET)CO2 has no changes and LC decreased (9. 7%, P < 0. 05) afterTrendelenburg’s position. Insuffiation of CO2 into the abdomen for 30 minutes causedmarked decrease in LC (25. 8, P<0. 01)and increase in PIP (17%,P<0. 05)and P(ET)CO2were not further increased , but LC further decreased (34. 2 %,P<0. 01).
出处 《中国普通外科杂志》 CAS CSCD 1995年第5期280-281,共2页 China Journal of General Surgery
关键词 胆囊切除 肺功能 腹腔镜 Lung compliance, Pulmonary function, Laparoscopy
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