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糖尿病患者血中降钙素和甲状旁腺激素水平的变化及其临床意义 被引量:7

SERUM LEVELS OF CALCITONIN AND PARATHYROID HORMONE IN DIABETIC PATIENTS
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摘要 本文共观测了51例糖尿病患者血中钙(Ca)、磷(P)、碱性磷酸酶(AKP)、甲状旁腺激素(PTH)、降钙素(CT)及血糖水平的变化。与正常对照组相比,在糖尿病各组中血Ca、P水平正常;AKP活性及PTH水平明显升高;在病情较重的糖尿病中血CT水平下降。糖尿病患者血PTH水平升高和CT水平的下降是机体的一种代偿调节,以使血Ca、P水平维持正常,但这种变化可以引起糖尿病性骨质疏松。 The serum levels of calcium, phosphate, parathyroid hormone, calcitonin, glucose and activity of alkaline phosphatase were investigated in 51 diabetic patients. In the patients, serum calcium and phosphate were normal; activity of serum alkaline phosphatase and serum patithyroid hormone were increased (both P<0.05). The decreased serum level of calcitonin (P<0.05) occured in the severe patients. In patients with diabetes mellitus the increased serum parathyroid hormone and decreased serum calcitonin might reflect a compensated regulation which maintain the serum levels of calcium and phosphate in the normal range, but lead to diabetic osteoporosis.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 1989年第3期139-140,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 糖尿病 降钙素 甲状旁腺激素 Diabetes mellitus Parathyroid hormone Calcitonin Metabolism of calcium and phosphorus
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参考文献3

  • 1余爱琴,伍汉文,黄海萍,朱淑华.糖尿病人钙磷代谢平衡试验的研究[J]天津医药,1981(08).
  • 2张昌颖.生物化学[M]人民卫生出版社,1985.
  • 3Dr. M. J. Atkinson,T. Schettler,H. Bodenstein,R. -D. Hesch. Osteoporosis: A bone turnover defect resulting from an elevated parathyroid hormone concentration within the bone-marrow cavity?[J] 1984,Klinische Wochenschrift(3):129~132

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