摘要
目的探讨慢性阻塞性肺疾病(COPD)合并肺癌早期诊断与治疗方法。方法对45例COPD合并肺癌患者的临床表现、早期诊断方法及选择的治疗方法进行分析。结果 13例患者经电子纤维支气管镜检查确诊,11例经肺穿刺活检证实,9例经痰细胞学证实,7例经淋巴结活检证实,5例胸腔积液病理学证实。所有患者均给予支气管扩张剂及糖皮质激素联合制剂治疗,其中手术治疗6例,存活5例(83.3%),化疗和(或)放疗30例,存活7例(23.3%),两者存活率有明显差异。结论 COPD患者合并肺癌的症状无特异性,早期确诊率低。COPD患者伴胸痛、血痰、胸腔积液、进行性消瘦应警惕合并肺癌的可能;行纤维支气管镜、穿刺活检或痰脱落细胞学检查对COPD合并肺癌的早期发现有一定的临床意义;手术可作为COPD合并肺癌的主要治疗方法,其次是放疗或是化疗。
Objective To explore the early diagnosis and treatment of chronic obstructive pulmonary disease (COPD) mergered lung cancer.Methods A total of 54 patients with COPD mergered lung cancer were analysed,including clinical feature,early period diagnosis and treatment options.Results 13 patients via e-fiberoptic bronchoscopy confirmed,11 cases confirmed by lung biopsy,9 patients with sputum cytology confirmed,lymph node biopsy in 7 cases,five cases of pleural pathology.All patients were treatmented with bronchodilator agents combined with glucocorticoid,of 6 cases were given surgical treatment,survival in 5 cases (83.3%),30 cases were treated with chemotherapy and /or radiotherapy,survived in 7 cases (23.3%).Conclusion There were no specific symptoms in the patients with chronic obstructive pulmonary disease (COPD) mergered lung cancer,so early period diagnosis rate was very low.Patients with COPD companied chest pain,sputum blood,hydrothorax and creasing thinness should alert the possibility of mergered lung cancer.Fiberoptic bronchoscopy,needle biopsy or sputum cytology play an importment role in the early detection of COPD with lung cancer.surgery can be used as the main treatment,followed by radiotherapy or chemotherapy in the treatment of COPD with lung cancer.
出处
《实用心脑肺血管病杂志》
2010年第12期1819-1820,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
慢性阻塞性肺病
肺癌
研究
Chronic obstructive pulmonary disease
Lung cancer
Research
