摘要
目的探讨癫痫持续状态后患者的认知功能及其影响因素.方法收集20例癫痫持续状态后患者作认知功能评估,并与正常对照组对照,分析影响认知功能的相关因素.认知功能评估采用简明精神状态量表,韦氏成人智力量表(WAIS-R)中的数字广度,数字符号转换测验,连线测验,言语流畅性测验.结果 (1)认知功能特点:癫痫持续状态后患者的简明精神状态量表,WAIS-R中的数字广度测验,WAIS-中的数字符号转换测验,连线测验,言语流畅性测验得分均低于正常对照组,差异有统计学意义(P<0.05);(2)认知功能的影响因素:进行多重线性回归分析,受教育程度、年龄、服抗癫痫药数目是影响癫痫持续状态后患者认知功能的因素.其中受教育程度是主要影响因素.结论癫痫持续状态后患者存在认知功能损害;受教育程度、年龄、服抗癫痫药数目是癫痫持续状态后认知功能的影响因素,受教育程度是主要影响因素.
Objective To investigate the cognitive function and influencing factors in patients with status epilepticus.Methods We collected 20 cases of patients with status epilepticus,and compared them with the control group.We asscessed the cognitive function of them and analyzed the related influencing factors of cognitive function.Mini-mental state(MMSE),Digital span test(DST),Digital symbol test(DST),Trail making test(TMT),Verbal fluency test(VFT)were applied to evaluate the cognitive function of patients with status epilepticus.Results(1)Cognitive features:Neuropsychologic test scores of patients with status epilepticus were lower than normal control group by applying with MMSE,DST of WAIS-R,DST,TMT and VFT,and the differences were statistically significant(P<0.01).(2)Influencing factors of congnitive function:Level of education,age and the number of medication were the main factors affecting cognitive function of patients with status epilepticus by multivariate stepwise regression analysis,particular level of education was the most evident.Conclusions Patients with status epilepticus have cognitive impairment.Level of education,age and the number of drugs have an impact on cognitive function,and education level is the major influencing factor of cognitive function.
出处
《昆明医学院学报》
2011年第12期93-96,100,共5页
Journal of Kunming Medical College
基金
云南省科技厅联合专项基金资助项目(2008CD016)
关键词
癫痫持续状态
认知功能
神经心理学测验
Status epilepticus
Cognitive function
Neuropsychological tests
