摘要
目的研究化疗对淋巴瘤伴乙肝病毒感染患者肝功能的影响。方法回顾性病例分析,比较50例HBsAg(-)、20例HBsAg(+)和18例小三阳的恶性淋巴瘤患者化疗后肝功能变化情况。结果HBsAg(-)组、HBsAg(+)组和小三阳组化疗后Ⅲ级以上肝功能损害分别是0%、15%、55%。结论伴乙肝病毒感染的淋巴瘤患者化疗后肝功能损害明显,尤其小三阳患者损害更为严重,甚至死亡。
Objective To study the effect of liver function during chemotherapy in malignant lymphoma patients with the HBV infection. Methods 50 cases with malignant lymphoma without positive serum HBsAg marker HhsAg（ - ） group were retrospectively matched in comparison with 20 cases with malignant lymphoma with positive serum HBsAg marker HbsAg （ ＋ ） group and 18 cases in three small positive group. Liver functions after chemotherapy of HBsAg （ - ） group were compared with that of HBsAg （ ＋ ） group and three small positive groups. Results After chemotherapy, the liver function severe damage rates in HBsAg （ - ） group, HBsAg （ ＋ ） group and three small positive groups were 0% , 15% and 55% respectively. Conclusion The cases of malignant lymphoma with HBV were more likely to have liver function damage in chemotherapy, the cases with three small positive were worse and even dead.
出处
《河南肿瘤学杂志》
2005年第5期321-322,共2页
Henan Journal of Oncology
关键词
恶性淋巴瘤
乙肝病毒感染
化疗
肝功能损害
malignant lymphoma
infection of hepatitis B virus
chemotherapy
liver function damage
