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胃肠道间质瘤22例诊治体会 被引量:4

The Experience of Diagnosis and Treatment of 22 Patients with Gastrointestinal Stromal Tumor(GIST)
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摘要 目的:总结胃肠道间质瘤诊断及治疗经验。方法:回顾性分析1999年6月~2004年10月间收治的22例胃肠道间质瘤的临床资料。结果:本组胃肠道间质瘤22例,其中11例位于胃,7例位于小肠,2例位于盲肠,1例位于结肠脾曲,1例位于小肠肠系膜。临床表现主要为消化道出血(9/22)、腹部包块(6/22)、腹痛(4/22)、贫血(3/22)手术前确诊1例。22例均行手术治疗。恶性7例,良性11例,交界性4例。随访2-66个月,死亡2例,1例死于腹腔广泛转移,1例死于心肌梗死。结论:胃肠道间质瘤临床表现无特异性,术前确诊率低。手术切除是明确诊断及治疗的主要方法。外科手术治疗宜及早进行。 Objective: To summarize the experience of diagnosis and treatment of GIST. Methods: The clinical data of 22 patients with GISTs from June 1999 to October 2004 were analyzed retrospectively. Results: Among 22 cases with GISTs, 11 cases originated in the stomach, 7 cases in the small intestine, 2 cases in the caecum, and 1 case in the left colic flexure, 1 ease in the mesentery. The main clinieal manifestations were gastrointestinal bleeding(9/22),abdominal mass(6/22),abdominal pain(4/22). 3 eases were found anemia and 1 ease was confirmed before operation. All 22 cases underwent surgical operation. 11 benign eases, 7 malignant cases and 4 bordline cases. All eases were followed up from 2 to 66 months, 2 eases died, one died from acute myocardial infarction, another died from diffuse abdominal metastasis. Conclnsion:GISTs have no specific clinieal characteristics, the diagnosis before operation is difficult. Surgical resection is the most important method for diagnosis and treatment of GISTs, and operation should be done as early as possible.
出处 《中国临床医学》 北大核心 2005年第4期620-621,共2页 Chinese Journal of Clinical Medicine
关键词 胃肠道 间质瘤 Gastrointestinal Strornal tumors
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参考文献3

  • 1Sircar K, Hewlett BR, Huizinga JD, et al. Interstitial cells of Cajal as precursors for gastrointestinal stromal tumors[J]. Am J Surg Pathol,1999,23(4) :377.
  • 2纪元,潘文生.胃肠道间质瘤临床病理研究进展[J].中国临床医学,2001,8(6):693-695. 被引量:13
  • 3Emory TS, Sobin LH, Lukes L, et al. prognosis of gastrointestinal smooth-muscle(stromal)tumors:dependence on anatomic site[J]. Am J Surg Pathol, 1999,23(1) :82.

二级参考文献18

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