摘要
目的探讨骨髓组织活检在全血细胞减少症中的临床作用。方法选常规骨髓穿刺部位,对21例全血细胞减少患者采用骨髓活检针取骨髓活检组织,应用塑料包埋法处理后进行HGF和纤维染色、光镜形态学观察分析,以确定21例骨髓涂片不能明确诊断的全血细胞减少患者的诊断。结果21例全血细胞减少患者骨髓活检结果提示,多数骨髓增生程度为活跃或明显活跃,少数增生低下;诊断以骨髓增生异常综合征(MDS-RCMD)最多见,占71.4%(15/21),慢性再生障碍性贫血、急性白血病、多发性骨髓瘤、骨髓纤维化各1例,诊断不确定、需结合临床分析者2例。结论骨髓活检塑料包埋技术能正确反应骨髓组织结构、细胞分布情况,在全血细胞减少症鉴别诊断具有重要意义。
Objective To explore the clinical effect of bone marrow biopsy on differential diagnosis for patients with pancytopenia. Methods Myeloid tissues of 21 patients with pancytopenia were taken by myeloid biopsy needle in conventional site of bone marrow aspiration. Blades of myeloid tissue were analysed carefully. Results Bone marrow biopsy imply that most of patients have active or obviously active hyperplasy degree. In 21 patients, there are 15 patients are diagnosed myelodysplastic syndrome,4 patients are diagnosed chronic aplastic anemia,acute leukemia, multiple myeloma and myelofibrosis respectively,2 patients are acatalepsy. Conclusion Bone marrow biopsy could reflect structure of myeloid tissues and distributoin of cells. It has important signficanoe on differential diagnosis of pancytopenia.
出处
《重庆医学》
CAS
CSCD
2005年第9期1293-1294,共2页
Chongqing medicine
