摘要
目的探讨护理干预在中晚期鼻咽癌(NPC)同期放疗、化疗中的作用。方法将110例初治的III期NPC患者随机分为同期放、化疗组(观察组)和单纯放疗组(对照组),观察两组的疗效及毒副反应,根据不同的毒副反应采取相应的护理措施并观察其效果。结果两组均能按计划完成了治疗,但观察组毒副反应较对照组重,给予积极的护理措施能减轻患者的心理压力和放、化疗毒副反应。近期疗效:鼻咽部原发灶CR率两组相似(p>0.05),颈部淋巴结转移灶CR率观察组较对照组高(p<0.05);远期疗效:5年生存率观察组较对照组高。结论同期放、化疗可以提高鼻咽癌颈部淋巴结转移灶的近期疗效和提高期III期NPC的5年生存率,但放疗、化疗的毒副反应较重,治疗中采取积极的护理措施能调动患者的主观积极因素,提高患者对治疗的配合程度和对治疗的耐受性,能减轻放射性口腔炎和射野皮肤反应,预防或减少并发症的发生,对顺利完成治疗和提高治疗效果起到了重要作用。
objective To explore the effect about nursing intervention on combined radiotherapy and chemotherapy of advanced Nasopharyngeal carcinoma. Methods 110 cases of stage Ⅲ nasopharyngeal carcinoma were randomly assigned to study group which was combined radiotherapy and chemotherapy and control group was subjected to radiotherapy simply . To study the therapeutic efficacy and toxic side effects .according to different toxic side effects we adopted corresponding nursing measures and observed the effects. Results All cases could smooth complete therapy according to plan but toxic side effects in the studying group were worse that of the control group .the patients can relieve their psychogyical press and toxic side effects when they were given the positive nursing measures shortterm effects showed the same CR rate of the primary nasopharyngeal focus （p〈0.05 ）.Long-term effects showed the CR rate of neck lymphatic metastasis focus and 5-year survival rate in the study group were higher than that of the control group. Conclusion Combined radiotherapy and chemotherapy could significantly increase the short-term effects and 5-year survival rate but the toxic side effects were severe .Nursing measures could mobilize the patients subjective positive factors and improve the patients who cooperated and received therapy. It was reduced radialized oral mucositis and skin reaction and prevented or decreased complication, It was an important action to smooth complete all therapy and improve the effect.
出处
《国际医药卫生导报》
2005年第17期207-210,共4页
International Medicine and Health Guidance News
