摘要
目的比较腹腔镜阑尾切除术(laparoscopic appendectomy,LA)和传统阑尾切除术(open appendectomy,OA)治疗小儿阑尾炎创伤反应的差异。方法从2002年5月至2004年2月收治160例小儿阑尾炎,其中行LA69例,OA91例,术前和术后12h采血,应用酶链免疫吸附试验测定血清白介素6(IL-6)和C反应蛋白(CRP)水平。结果手术时间:LA组(33±15)min比OA组(45±9)min短(t=6·40,P<0·01);住院时间:LA组(4·3±1·5)d比OA组(6·6±1·2)d短(t=10·91,P<0·01)。术后切口感染:LA组1例(1·5%),OA组10例(11·0%),两者之间差异有统计学意义(χ2=4·19,P<0·05)。OA组IL-6术后较术前升高值明显高于LA组[(60±20)pg/ml比(28±8)pg/ml,P<0·01]。CPR在OA组术后升高值亦明显高于LA组[(83±11mg/L比(24±6)mg/L,P<0·01]。结论LA治疗小儿阑尾炎较OA手术时间短、创伤小、恢复快、并发症少。
Objective To comparatively study the surgical stress caused by laparoscopic appendectomy （LA） and open appendectomy（OA） in children. Methods Sixty-nine underwent LA and 91 did OA. Serum IL-6 and CRP levels were measured before and 12 h post-op. Results The operative time was significantly shorter in laparoscopic group（ 33 ± 15 min vs 45 ± 9 min, P 〈 0.01 ）. Hospital stay in LA group was shorter [ （4. 3 ± 1.5） days vs （6. 6 ± 1.2） days, P 〈0. 01 ]. Wound infection occurred in one patient （ 1.5% ） in LA group, and in ten （ 11.0% ） in OA group （P 〈0. 05）. Postoperative increase of IL-6 in OA group was higher than that in LA group [ （60 ±20） pg/ml vs （28±8） pg/ml, P 〈0. 01 ]. The postoperative rise of CRP in OA group was also higher compared with that in LA group [ （83 ±11 ） mg/L vs （ 24± 6 ） mg/L, P 〈 0. 01 ]. Conclusions LA for children is as safe and effective as the open procedure with additional benefits of shorter operating time, less surgical trauma and rapid postoperative recovery.
出处
《中华普通外科杂志》
CSCD
北大核心
2005年第9期589-590,共2页
Chinese Journal of General Surgery
