摘要
目的探讨重症急性胰腺炎(SAP)合并深部真菌感染的特点和防治。方法回顾241例SAP患者的临床特点,其中合并深部真菌感染46例,给予及时静脉输注氟康唑200mg,每天2次,疗程5～15d,其中34例同时行手术清除病灶。结果急诊手术18例,中转手术16例,保守治疗成功12例,存活40例,治愈率为87%,致残2例(失明),死亡6例。结论真菌感染是重症急性胰腺炎的严重并发症,发病率及病死率均较高;早期诊断与及时治疗可获得较好的疗效。
Objective To investigate the clinical character of patients with severe acute pancreatitis infected with fungal organisms and its prevention and treatment. Methods Among 241 patients with severe acute pancreatitis,46 cases with severe acute pancreatitis and fungal infection were treated with fluconazole（100mg, 3 times per day for 5-15 days） ,thirty-four cases of that received operation about cleaning out focus synchronously. Results Eighteen cases were given emergency operation; 16 cases accepted operation midway. Twelve patients were cured by nonsurgery. Forty cases were alive. Cure rates were 87 % . Two cases were disabled（blindness）, and 6 cases died. Conclu- sion Fungal infection is a severe complication of severe acute pancreatitis,which had a high morbidity and mortality. Early diagnosis and timely treatment may achieve satisfactory therapeutic effects.
出处
《中国基层医药》
CAS
2005年第9期1135-1136,共2页
Chinese Journal of Primary Medicine and Pharmacy
