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产超广谱β-内酰胺酶肺炎克雷伯菌分子流行病学研究进展 被引量：2

Progress in molecular epidemiological studies of extended-sputum beta-lactamaseproducing Klebsiella pneumonia
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摘要 产超广谱β-内酰胺酶(ESBLs)是导致肺炎克雷伯菌耐药的主要原因。现对其基因分型、检测方法及产超广谱β-内酰胺酶肺炎克雷伯菌分子流行病学研究作一综述。
作者 刘朝晖 陈劲龙 冉丕鑫
机构地区 广州市第一人民医院内科
出处 《国外医学（临床生物化学与检验学分册）》 2005年第9期606-608,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
关键词 克雷伯菌 肺炎 Β内酰胺酶类 分子流行病学 产超广谱Β-内酰胺酶 分子流行病学研究 肺炎克雷伯菌 基因分型
分类号 R181.3 [医药卫生—流行病学]
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参考文献15

  • 1Quale JM,Landman D,Bradford PA,et al. Molecular epidemiology of a citywide outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae infection.Clin Infect Dis,2002,35(7):834-841.
  • 2Tzelepi E,Magana Ch,Platsouka E,et al.Extended-spectrum beta-lactamase types in Klebsiella pneumoniae and Escherichia coli in two Greek hospitals. Int J Antimicrob Agents,2003,21(3):285-328.
  • 3Pagani L,Perilli M,Migliavacca R,et al.Extended-spectrum TEM- and SHV-type beta-lactamase-producing Klebsiella pneumoniae strains causing outbreaks in intensive care units in Italy. Eur J Clin Microbiol Infect Dis,2000,19(10):765-772.
  • 4Coque TM,Oliver A,Pérez-Díaz JC.Genes Encoding TEM-4,SHV-2,and CTX-M-10 extended-spectrum beta-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital(Madrid,1989 to 2000). Antimicrob Agents Chemother,2002,46(2):500-510.
  • 5Barroso H,Freitas-Vieira A,Lito LM,et a1.Survey of Klebsiella pneumoniae producing extended-spectrum beta-lactamases at a Portuguese hospital:TEM-10 as the endemic enzyme.J Antimicrob Chemother,2000,45(5):611-616.
  • 6Palucha A,Mikiewicz B,Hryniewicz W,et al. Concurrent outbreaks of extended-spectrum beta-lactamase-producing organisms of the family Enterobacteriaceae in a Warsaw hospital.J Antimicrob Chemother,1999,44(4):489-499.
  • 7Paterson DL, Hujer KM,Hujer AM,et al.Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-type beta-lactamases. Antimicrob Agents Chemother,2003,47(11):3554-3560.
  • 8Yamasakl K,Komatsu M,Yamashita T,et a1.Production of CTX-M-3 extended-spectrum {beta}-lactamase and IMP-1 metallo {beta}-lactamase by five Gram-negative bacilli: survey of clinical isolates from seven laboratories collected in 1998 and 2000, in the Kinki region of Japan.Clin Infect Dis,2002,35(7):834-841.
  • 9Kim J,Kwon Y,Pai H,et a1.Survey of Klebsiella pneumoniae Strains Producing Extended-Spectrum beta -Lactamases: Prevalence of SHV-12 and SHV-2a in Korea. J CIin Microbiol,1998,36(5):1446-1449.
  • 10Pai H,Lyu S,Lee JH,et al. Survey of Extended-Spectrum beta -Lactamases in Clinical Isolates of Escherichia coli and Klebsiella pneumoniae: Prevalence of TEM-52 in Korea. J Clin Microbiol,1999,37(6):1758-1763.

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国外医学（临床生物化学与检验学分册）
2005年 第9期

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