摘要
目的探讨胰岛素抵抗与腔隙性脑梗死的相关关系及其可能机制。方法选取47例脑梗死患者,分为腔隙性脑梗死组(23例),非腔隙性脑梗死组(24例),设立正常对照组。测定3组的空腹血糖、空腹血胰岛素、血脂及计算其胰岛素敏感性指数。结果腔隙性脑梗死组胰岛素敏感性指数较对照组及非腔隙性脑梗死组低(P<0.05),空腹血胰岛素、甘油三酯较其他两组高(P<0.05)。结论胰岛素抵抗与腔隙性脑梗死关系密切。
Objective To study the relationship between insulin resistance and lacunar infarction,then to discuss its possible mechanisms.Methods 47patients with stroke were divided into lacuna infarction group （LI,23cases） and non-lacuna group （ NLI, 24 cases）. The normal control group had 24 people. Their fasting plasma glucoses, seruin insulin, seruin lipids were measured and their insulin sensitivity indexes（ISI） calculated. Results ISI of LI group were significantly lower than NLI group and normal control group （ P 〈 0. 05 ）. The plasma level of TG and insulin in LI group were significantly higher than those in two other groups（ P 〈 0. 05 ）. Conclusion There is an strong relationship between IR and lacuna infarction.
出处
《中国临床保健杂志》
CAS
2005年第5期414-415,共2页
Chinese Journal of Clinical Healthcare
关键词
胰岛素抗药性
脑梗塞
血糖
高脂血症
Insulin resistance
Brain infaction
Blood glucose
Hyperlipidemia
