摘要
为探讨脑出血与脑梗塞时颅内外动脉病变的异同点，对４２例脑出血、５８例脑梗塞与２０例对照病例的颅底中型动脉及主要分支、脑内小动脉、微动脉与颅外颈动脉（１４例）进行了病理观察，同时利用图像分析系统对动脉的面积比值及口径狭窄度做了定量分析。结果显示：（１）脑出血、脑梗塞组较对照组颅内四级动脉的面积比值都显著减少（Ｐ＜０．０１）；（２）脑出血组比脑梗塞组脑内小动脉、微动脉的面积比值显著减少（Ｐ＜０．０１）；（３）脑梗塞组比脑出血组颅底中型动脉及主要分支的面积比值显著减少（Ｐ＜０．０１，Ｐ＜０．０５），而动脉口径狭窄度显著增加（Ｐ＜０．０１，Ｐ＜０．０５）；（４）脑梗塞组颈动脉口径的狭窄度较脑出血组增加。提示：脑中风患者颅内各级动脉都存在显著病变。但是，脑出血的主要病变部位在脑内小动脉、微动脉。脑梗塞的主要病变部位在颅底中型动脉及主要分支，其次为颅外颈动脉。
Inordertocomparethediferenceandsimilarityofthepathologicalchangesinintracra-nialandextracranialarteriesbetweencerebralhemorrhage(CH)andcerebralInfarction(CI),120au-topsyca-seswerestudied,including42casesoftheCH,58casesoftheCIand20casesofcancerascontrol.Mediumsizedintracranialarteriesandtheirmainbranches,smalsizedintracerebralarteries,arteriolesandextracranialcarotidarteries(from14casesonly)wereexaminedwithlightmicroscopy.Theratiooflumenareatovesselarea(LA-VAratio)andthedegreeofnarrowingofthevesselsindicat-ingtheseverityofarteriosclerosisweredetermined.Quantitativeanalysiswascariedoutwithcomput-er.Theresultswereasfolows:(1)TheCHandCIpatientshadsignificantlylowermeanLA-VAra-tiosofthemediumintracranialarteriesandtheirmainbranches,smalintracerebralarteriesandarteri-olesthanthecontrols.(2)TheCHpatientshadapparentlylowerLA-VAratioofthesmalintracere-bralarteriesandarteriolesthantheCIpatients.(3)TheCIpatientshadsignificantlylowerLA-VAra-tioofthemediumsizedintracranialarteriesandtheirmainbranchesthantheCHpatients.Moreover,atheroscleroticnarowingofthesevesselswasalsomuchmoresevereintheCIthanintheCHpatients.(4)AtheroscleroticnarrowingoftheextracranialcarotidarteryintheCIpatientswasslightlymorese-verethanthatintheCHpatients.Thesedatasuggestthatpatientswithcerebralstrokehavefrequentlyatheroscleroticlesionsinthemediumsizedintracranialarteriesandtheirmainbranchesandscleroticle-sionsinthesmalintracerebralarteriesandarterioles.TheprincipallesionoftheCHareinthesmalintracerebralarteriesandarterioles,whilethoseoftheCIinthemediumsizedintracranialarteriesandtheirmainbranchesandsometimesintheextracranialcarotidarteries.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1996年第8期513-516,共4页
Chinese Journal of Internal Medicine
基金
解放军八五科研基金
