期刊文献+

系统性红斑狼疮脑病的MRI诊断与病理 被引量:5

在线阅读 下载PDF
导出
摘要 目的:探讨系统性红斑狼疮脑病(LEE)的MRI征象、病理及其临床诊断价值。方法:回顾性分析28例LEE患者的MRI资料。患者年龄14~51岁,病史1~8年,所有病例均符合系统性红斑狼疮的诊断,临床以神经精神异常而行颅脑MR检查。结果:本组颅脑MRI表现为单侧或双侧额、顶枕或颞枕皮层下白质内异常信号25例,病灶表现为斑点、条状及片状影,T1加权像为等或稍低信号,T2加权像为高信号;局灶性异常信号6例,其中3例合并病灶内出血;弥漫性中度以下脑萎缩6例。结论:MRI检查对LEE有较高的敏感性,能明确病灶的部位和范围,结合临床资料,MRI可以诊断LEE,并在指导治疗及评价疗效方面有重要意义。
出处 《实用医学杂志》 CAS 2005年第19期2170-2171,共2页 The Journal of Practical Medicine
  • 相关文献

参考文献6

二级参考文献33

  • 1Miguel EC, Pereira RM, Pereira CA, et al. Psychiatric manifestations of systemic lupus erythematosus: clinical features, symptoms and signs of central nervous system activity in 43 patients. Medicine-Baltinmore,1994, 73:224.
  • 2Weingarten K, Filippi C, Barbut D, et al. The neuroimaging features of the cardiolipin antibody syndrome. Clin Imaging, 1997, 21:6.
  • 3Bell CL, Partington C, Robbins M, et al. Magnetic resonance imaging of central nervous system lesions in patients with lupus erythematosus:correlation with clinical remission and antineurofilament and anticardioliolipin antibody titers. Arthritis Rheum, 1991, 34:432.
  • 4Waterloo K, Omdel R, Jacobsen EA, et al. Cerebral computered tomography and electroncephalography compared with neuropsychologic findings in systemic lupus erythematosus. J-Neurol, 1999, 246:706.
  • 5McCune WJ, MacGuire A, Aisen A, et al. Identification of brain lesions in neuropsychiatric systemic lupus erythematosus by magnetic resonance scanning. Arthritis and Rheumatism, 1998, 31:159.
  • 6Kozora E, West SG, Kotzin BL,et al. Magnetic resonance imaging abnormalities and cognitive deficits in systemic lupus erythematosus patients without overt central nervous system disease. Arthritis Rheum,1998, 41:41.
  • 7Raymond AA, Zariah AA, Samad SA, et al. Brain calcification in patients with cerebral lupus. Lupus, 1996, 5:123.
  • 8Fotini B, Ioannidis J, Kyriaki A, et al. Predictors of Clinical Outcome and Radiologic Progression on Patients with Neuropsychiatric Manifestations of Systemic Lupus Erythematous. Am J Med, 2000, 109(8): 628-634
  • 9SannaG, Piga M, Pelty MT, et al. Central nervous system involvement in systemic lupus erythematosus: cerebral imaging and serological profile in patients with and without overt neuropsychiatric manifestations. Lupus, 2000, 9(8): 573-583
  • 10Sibbitt WL, Saibbit RR, Brooks WM, et al. Neuroimaging in Neuropsychiatric Systemic Lupus Erythematosus. Arthritis Rheum, 1999, 42(10): 2026-2038

共引文献34

同被引文献52

引证文献5

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部