摘要
目的:观察生脉注射液在恶性肿瘤化疗中减轻骨髓抑制、恶心呕吐等毒副反应的疗效。方法:治疗组采用生脉注射液60ml+5%葡萄糖500ml静脉滴注,每日1次,连用15天为1周期,在化疗开始前2天开始用药。对照组仅用化疗。所有病例均接受2周期化疗。结果:治疗组白细胞降低的例数及程度都明显优于对照组,两组有显著性差异(P<0.05)。治疗组与对照组在恶心、呕吐反应方面无显著性差异(P>0.05),但治疗组重度呕吐比例稍低。结论:生脉注射液在恶性肿瘤化疗时对骨髓抑制和胃肠道反应都有明显的预防和治疗作用,该药对中晚期肿瘤患者的化疗减毒有效。
Objective：To observe ShengMai injection decreasing toxic reaction of nausea and vomiting in tumor chemotherapy. Methods： Patients in the treatment group accepted 60ml ShengMai injection and 500ml 5 % glucose infusion intravenously from the second day after chemotherapy, once daily, 15 days continuously was one cycle. Control group accepted only chemotherapy. All patients accepted chemotherapy for two weeks. Results： Number and degree of leukocyte decrease in treatment group were obviously superior to control group （P 〈 0. 05 ）. There were no significant difference between therapy and control group in nausea and vomiting reaction （P 〉 0. 05）, but a few patients in treatment group had severe vomiting. Conclusion： ShengMai injection had obviously preventive and therapeutic effects on bone marrow depression and gastrointestinal reaction when patients received chemotherapy, the drug had attenuate effect in chemotherapy of middle-late patients.
出处
《临床肿瘤学杂志》
CAS
2005年第2期159-160,共2页
Chinese Clinical Oncology
关键词
生脉注射液
恶性肿瘤
化疗
减毒
Shengmai injection
Tumor
Chemotherapy
Attenuate effect
