摘要
目的:评价激光焊接齿科镍铬-钴铬合金的生物相容性。方法:参照GB/T16886技术报告相关标准,对激光焊接齿科镍铬-钴铬合金生物相容性进行体内及体外试验,包括细胞毒性试验、短期急性全身毒性试验及口腔黏膜刺激试验。结果:激光焊接齿科镍铬-钴铬合金细胞毒性实验评价级别为1级,无明显细胞毒性作用,未见任何急性毒性反应,口腔黏膜刺激试验未见异常组织学反应。结论:激光焊接齿科镍铬-钴铬合金具有良好生物相容性,安全无毒。
Objective： To evaluate the biological compatibility of laser-welded dissimilar alloy in dentistry： Co-Cr and Ni-Cr alloy. MethOdS： Cytotoxicity, acute toxicity and mucous membrane irritation were performed on the laser-welded dissimilar alloy in dentistry： Co-Cr and Ni-Cr alloy based on GB/T 16886 standard. Results： The results showed that the level of cytotoxicity was grade 1, no obrious cytotoxicity no acute toxicity and no histomorphologic changes were observed in mucous membrane. Conclusion： The laser-welded dissimilar alloy in dentistry： Co-Cr and Ni-Cr alloy has a good biocompatibility, and is safe and nonpoisonous.
出处
《天津医药》
CAS
北大核心
2005年第12期777-779,共3页
Tianjin Medical Journal
基金
天津市自然科学基金资助项目(项目编号:043601111)
关键词
激光
牙科合金
铬合金
生物相容性材料
lasers dental alloys chromium alloys biocompatibility materials
