摘要
[目的]观察疏血通注射液对脑动脉硬化症患者的临床疗效,并探讨其作用机制。[方法]将106例脑动脉硬化症患者随机分为治疗组和对照组各53例,治疗组予疏血通注射液静脉滴注,加服肠溶阿斯匹林;对照组予口服西比灵和肠溶阿斯匹林。15天为1个疗程,连续治疗2个疗程后观察两组的临床疗效及血浆一氧化氮(NO)和内皮素(ET)的水平。[结果]治疗组眩晕、头痛和耳鸣等症状的改善优于对照组(P<0.05);两组NO水平均有升高,ET水平均有下降,但治疗组效果优于对照组(P<0.05)。[结论]疏血通注射液对脑动脉硬化症患者疗效显著;其作用机制可能是通过调节血管活性物质而发挥作用。
[Objective] To observe the effects of treating cerebral arteriosclerosis mainly with Shu Xue Tong Injection, and probe into its mechanism. [ Methods] 106 cases of cerebral arteriosclerosis were randomly divided into two groups, The treatment group with 53 cases was treated with Shu Xue Tong Injection and aspirin tablet, while the control group with sibelium and aspirin tablet. The treatment course lasted 15 days. Then the curative effects, the level of NO and ET were observed alter 30 days. [Results] Compared to the control group, the symptoms as dizziness, headache and tinnitus were obviously improved in the treatment group（P〈0.05）. Meanwhile, better effects were achieved in the treatment group on increasing the NO level and lowering the ET level（P〈 0.05 ）, [ Conclusions] Shu Xue Tong Injection has distinctive effects on cerebral arteriosclerosis probably by regulating the vaso-active substance.
出处
《广西中医学院学报》
2005年第4期1-3,共3页
Journal of Guangxi Traditional Chinese Medical University
