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热休克蛋白gp96与肿瘤免疫治疗 被引量:5

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摘要 热休克蛋白(HSP)gp96是一种高度保守的蛋白质,具有分子伴侣功能,参与MHC-Ⅰ类抗原的提呈。肿瘤来源的gp96-肽复合物免疫活性强,可诱发抗相应肿瘤细胞的MHC-Ⅰ类限制性 CD8+细胞毒性T细胞免疫应答,为肿瘤免疫治疗开辟了一条新的途径。
作者 吕蔡 张杰
出处 《国际肿瘤学杂志》 CAS 2006年第1期1-4,共4页 Journal of International Oncology
基金 国家自然科学基金资助项目(303711325)
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