摘要
[目的]研究芦荟凝胶浆对小鼠免疫功能的影响。[方法]雌性ICR小鼠192只，体重18～23g，按体重随机分成对照组和5．7、11．4、34．2ml／kg体重3个剂量组，小鼠经口灌胃给予芦荟凝胶浆30d后，分别测定免疫功能的7项指标。[结果]芦荟凝胶浆高剂量组小鼠的足跖肿胀度（0．41mm）与对照组（O．25mm）相比明显增高，低、中、高3个剂量组的抗体生成细胞数[（75.4、77．4、76．4）×10^3／全脾]明显高于对照组（54．8×10^3／全脾），中、高剂量组腹腔巨噬细胞吞噬百分率（36．5％、41．8％）和吞噬指数（0．66、0．67）明显高于对照组（23．8％、0．35），中、高剂量组NK细胞活性（45．2％、44．3％）明显高于对照组（25．3％），中剂量组胸腺／体重比值（0．31）明显高于对照组（0．24）。[结论]芦荟凝胶浆能增强小鼠的细胞免疫功能、体液免疫功能、单核-巨噬细胞功能和NK细胞活性。
[Objective]To study the effects of alogs juice on immune functions in mice. [Methods]aloe＇s juice was administered to 4 groups of female ICR mice by gavage in doses of 0,5.7,11.4,34.2 ml/kg BW for 30 days. 7 indexes of immune system including the cellular immunity,the humoral immunity,macrophagocyte phagocytosis function and the activity of NK cell were examined. [Resuits]Tumefaction degree of mouse foot vola in 34.2 ml/kg BW group increased significantly compared with that of the control group （P〈0.01）. The number of antibody-producing cell in 5.7,11.4,34.2 ml/ kg BW groups were all higher than those of the control group. （P〈0.05）.The abitity Of macrophagocyte phagocytosis in abdominal cavity and the activity of NK cell in 11.4,34.2ml/kg BW groups were all raised significantly（ P 〈0.01, P 〈 0.05）. The ratio of thymus/weight in 11.4 ml/kg BW group was higher than that of control group P〈0.05）. [Conclusion]Aloe＇s juice could strengthen cellular immune functions, humoral immune functions, macrophagocyte phagocytosis function and the activity of NK cell of mice.
出处
《预防医学论坛》
2006年第1期61-62,共2页
Preventive Medicine Tribune
