摘要
目的:分析不同精子来源和数量对单精子卵胞浆内注射术(ICSI)妊娠结局的影响。方法:2000年1月至2003年6月在本中心进行ICSI治疗而妊娠的271例,据精子来源与数量分为精液正常组(39例)、少弱精组(144例)与手术取精组(88例)。比较精液正常组、少弱精组、手术取精组的临床妊娠率、流产率、分娩率、妊娠并发症、分娩孕周、新生儿出生体重、畸形、围生儿死亡率等组间差异。结果:精液正常组、少弱精组与手术取精组患者的临床妊娠率、流产率、分娩率、双胎率、妊娠期高血压疾病发生率、前置胎盘发生率、早产率、分娩孕周、新生儿出生体重、先天性畸形发生率(4.5%、6.3%、4.0%)、围生儿死亡率差异均无显著性(P>0.05)。结论:精液正常组、少弱精组与手术取精组ICSI治疗后临床妊娠率、流产率、妊娠期并发症、新生儿出生体重、先天性畸形发生率、围生儿死亡率相似,不同精子来源与数量不影响ICSI治疗后的妊娠和围生儿结局。
Objiective： To analyze the effect of spermatoza origin and quantity on pregnancy outcome after intracytoplasmic sperm injection. Methods： A retrospective study was carried out to compare the rate of dinical pregnancy, pre-clinical and clinical abortion, delivery, pregnant complications, gestational age, and birth weight and mafformation of neonatal, perinatal mortality in women receMng normal semen （n = 39, group1）, oligoasthenozoospermis （n = 144, group2） and sperm obtained by surgery （n=88, group3） between January 2000 and June 2003. Results： The matemal age and infertile duration were comparable among three groups. There were no significant differences in rate of clinical pregnancy, abortion, birth, twin gestation, pregnancy-induced hypertension, placenta praevia, premature birth, gestational age when labor, congenital malformation, padnatal mortality （4.5% vs 6.3% vs 4.0%）and birth weight of neonatalamong three groups（P〉0.05）. Conclusions.. The pregnancy and padnatal outcome after ICSI is neither affected by the origin of sperm nor by the quantity of sperm in the ejaculate.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2006年第2期108-110,共3页
Journal of Practical Obstetrics and Gynecology
