摘要
目的总结原发性颈段气管肿瘤的诊治经验,提高治疗效果。方法回顾性分析1981年1月—2002年12月在中国医学科学院肿瘤医院头颈外科治疗的38例原发性颈段气管肿瘤患者的临床资料。手术治疗26例,单纯放疗12例。气管袖状切除11例;气管壁部分切除13例,其中Ⅰ期气管修复6例;全喉、部分气管和甲状腺腺叶切除2例。结果恶性肿瘤34例,其中腺样囊性癌19例,鳞状细胞癌10例,非霍奇金淋巴瘤2例,低分化癌1例,中分化腺癌1例,小细胞未分化癌1例。颈段气管腺样囊性癌患者3年和5年生存率分别为79·80%和48·36%,鳞状细胞癌分别为80·00%和20·00%。良性肿瘤患者均无瘤生存。治疗后并发症的发生率为18·4%(7/38),其中气管狭窄的发生率11·5%(3/26)。结论原发性气管肿瘤多数为恶性,其中以腺样囊性癌和鳞状细胞癌居多。手术治疗为气管肿瘤首选治疗措施,气管袖状切除为手术方式之一。
Objective To review the experience of diagnosis and treatment of primary cervical tracheal tumor. Methods Medical history records of 38 patients with primary cervical tracheal tumor who were treated at department of Head and Neck Surgery, Cancer Hospital, Chinese Academy of Medical Sciences between January 1981 and December 2002 were retrospectively analyzed. Twenty six patients underwent surgical resection, twelve patients received only radiotherapy. Eleven patients underwent sleeve tracheal resection, thirteen patients with partial tracheal wall resection and 6 of them with tracheal reconstruction immediately, two patients with total laryngectomy and resection of partial trachea and thyroid lobectomy. Results Thirty four patients had malignant tumors, among which 19 cases were adenoid cystic carcinoma and 10 cases squamous cell carcinoma. The 3-year and 5-year survival rate were 79. 80% and 48. 36% respectively for the patients with adenoid cystic carcinoma , 80. 00% and 20. 00% respectively for the patients with squamous cell carcinoma. The rate of complication was 18.4% （7/38）, among which tracheal stenosis was 11.5% （3/26）. Conclusions Most of primary cervical trancheal tumors were malignant, adenoid cystic carcinoma and squamous cell carcinoma were the common malignant cervical tracheal tumors. Surgery is the first choice for cervical tracheal tumors, and the sleeve trachea resection is one of the optimal surgical modality.
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2006年第3期208-210,共3页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
关键词
气管肿瘤
癌
腺样囊性
癌
鳞状细胞
诊断
综合疗法
存活率
Tracheal neoplasm
Carcinoma, adenoid cystic
Carcinoma, squamous cell
Diagnosis
Combined modality therapy
Survival rate
