摘要
目的了解短程化疗方案治疗合并糖尿病肺结核的效果,探讨合并糖尿病肺结核的抗结核疗程。方法回顾性分析1999—2004年在汕头市结核病防治所治疗的符合选例标准的78例合并糖尿病肺结核患者接受短程化疗的疗效。结果满疗程血糖控制良好组(Ⅰ组)痰菌阴转率92.3%,与同期接受短程化疗的单纯肺结核痰菌阴转率94.5%比较无显著性差异(P>0.05)。血糖控制不良组(Ⅱ组)痰菌阴转率为66.7%,Ⅰ组与Ⅱ组痰菌阴转结果比较,有显著性差异(P<0.05)。满疗程Ⅰ组与Ⅱ组病灶吸收好转率分别为89.5%和52.4%(P<0.01),空洞闭合率分别为67.6%和15.4%(P<0.01),2组病灶吸收好转率、空洞闭合率结果分别比较均有显著性差异。结论合并糖尿病肺结核患者中血糖控制良好者采用短程化疗方案治疗,近期效果良好,血糖控制差者,疗效较差;对血糖控制不良者或满疗程肺结核仍呈活动性者,应考虑适当延长疗程;早期诊断、早期合理抗结核及合理降糖治疗,对提高治疗效果有积极的意义。
Objective To evaluate the short-term effects of chemotherapy for the patients with tuberculosis and diabetes, and to evaluate the duration of treatment. Methods The data of 78 patients with tuberculosis and diabetes were collected retrospectively, and therapeutic effects were analyzed. Results At the end of the treatment, the sputum conversion rate of the plasma glucose controlled well group （group Ⅰ） was 92.3 %, while the sputum conversion rate of the group, that the patients suffer tuberculosis not with diabetes, was 94.5 %, there was no statistical difference （ P 〉 0.05）. The sputum conversion rate of the plasma glucose controlled fall group （group Ⅱ） was 66.7%, there was significant difference in statistics of group Ⅰ and group Ⅱ （P 〈 0.05）. The foci absorption rate of group Ⅰ was 89.5 %, the foci absorption rate of group Ⅱ was 52.4 %, two groups have a significant difference in statistics（ P 〈 0.01）. The cavity close up rate of group Ⅰ was 67.6%, the cavity close up rate of group Ⅱ was 15.4%, there was significant difference in statistics of two groups （ P 〈 0.01）. Conclusions If plasma glucose was controlled well, the short-term effects of chemotherapy in the patients who suffered tuberculosis and diabetes is good; if plasma glucose was controlled fall, the effects is worse. The patients whose plasma glucose controlled fall should prolong the treatment; at the end of treatment, whose tuberculosis is activity, also should prolong the treatment. Early diagnosis and treated tuberculosis and diabetes may yield the satisfactory resuits.
出处
《中国防痨杂志》
CAS
2006年第2期74-76,共3页
Chinese Journal of Antituberculosis
关键词
结核
肺/药物疗法
糖尿病
结核
肺/并发症
Pulmonary tubereulosis/drug therapy
Diabetes
Pulmonary tuberculosis/complication
