期刊文献+

肾移植治疗终末期肾衰竭伴纯红再障临床研究——附2例远期疗效随访报告及文献复习

Clinical Investigation on Uremic Patients with PRCA Treated by Renal Transplation Two Cases Reports and Literatures Review
在线阅读 下载PDF
导出
摘要 目的:通过总结2例终末期肾衰竭(ESRD)患者伴纯红再障(pureredcellaplasia,PRCA)的临床资料,介绍该病的诊断与治疗。方法:回顾性总结2例ESRD合并PRCA的诊治并复习相关文献。结果:2例ESRD患者均确诊为肾性贫血常规给予α-促红素(α-rhuEPO)治疗后出现PRCA。2例经肾移植术,随访3年以上,目前病情稳定。结论:使用促红素治疗ESRD所致肾性贫血出现的PRCA,其首选的治疗方法是肾移植。 Objective: Introduction of the diagnosis and the treatment of PRCA through the survey of 2 cases of uremic patients acquired PRCA. Methods: Respctively analyzing the date of two uremic patients with PRCA and reviewing relevant literature. Results:Two uremic patients who acquired PRCA after treatment with a - erythropoietin were healed by renal transplation and in steady recovery more than 3 years. Conclusion: Renal transplation is the initial choice for treatment of uremic patients with PRCA.
出处 《中国中西医结合肾病杂志》 2006年第4期223-226,共4页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 南京军区联勤第十八分部备案项目
关键词 终末期肾衰竭(尿毒症) 促红素 纯红再障 肾移植 ESRD(Uremic) rhuEPO Pure red cell aplasis Renal transplation
  • 相关文献

参考文献9

  • 1Bergrem H,Danielson BG,Eckardt KU,et al.A case of antierythropoietin antibodies following recombinant human erythropoietin treatment.In:Erythropoietin:Molecula Physiology and Clinical Application,edited by Bauer C,Koch KM,Scigalla P,New York,Marcel Dekker,1993.266-275.
  • 2Peces R,de la Torre M,Alcazar R,et al.Antibodies against recombinant human erythropoietin in a patient with erythropoietin-resistant anemia.N Engl J Med,1996,335(7):523-524.
  • 3Prabhakar SS,Muhlfelder T.Antibodies to recombinant human erythropoietin causing pure red cell aplasia.Clin Nephrol,1997,47(5):331-335.
  • 4Verhelst D,Rossert J,Casadevall N,et al.Treatment of erythropoietin-induced pure red cell aplasia:a retrospective study.Lancet,2004,363 (9345):1768-1771.
  • 5Netti GS,Petruzzelli V,Blasi A,et al.May recombinant erythropoietin induce a specific T-cell-mediated immune response.Nephrol Dial Transplant,2003,18 (Suppl 4):161.
  • 6Bunn HF.Drug induced autoimmune red cell aplasia.N Engl J Med,2002,346(7):522-523.
  • 7Cavill I,Williams JD.Benefits of recombinant human erythropoietin.Lancet,2002,360 (9345):1606-1607.
  • 8Weber G,Gross J,Kromminga A,et al.Allergic skin and systemic reactions in a patient with pure red cell aplasia and anti-erythropoietin antibodies challenged with different epoetins.J Am Soc Nephrol,2002,13(9):2381-2383.
  • 9Rossert J,Casadevall N,Eckardt KU.Anti-erythropoietin antibodies and pure red cell aplasia.J Am Soc Nephrol,2004,15(2):398-406.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部