摘要
目的评价超液化碘油、平阳霉素混合液和聚乙烯醇在子宫肌瘤栓塞的价值。资料与方法将110例子宫肌瘤患者分成两组进行栓塞治疗,其中A组(51例)采用超液化碘油和平阳霉素混合液作为栓塞剂,另外B组(59例)采用聚乙烯醇(直径300～700μm)作为栓塞剂,随访时间48～72个月[平均(36±6)个月],观察其疗效和并发症。结果A组月经量过多症状改善48/49,B组45/45;A组压迫症状改善13/13,B组11/11,两组没有统计学差异。A组栓塞后子宫体积减少(50.92±2.78)%;B组子宫体积减少(51.87±3.12)%,两组没有统计学差异(t值1.688,P>0.05)。A组栓塞后肌瘤体积减少(65.12±5.68)%;B组肌瘤体积减少(62.94±7.23)%,两组没有统计学差异(t值1.769,P>0.05)。两组栓塞前后性激素变化没有统计学差异。栓塞后一般轻度并发症发生率两组没有统计学差异。A组出现永久性卵巢性闭经3例,膀胱误栓1例,栓塞2年后肌瘤再发2例。B组栓塞2年后肌瘤再发2例。结论从中长期追踪观察来看,碘油、平阳霉素混合液和聚乙烯醇两种栓塞剂在子宫肌瘤栓塞中,疗效和栓塞后一般并发症发生方面没有统计学差异。但是由于碘油的液体特性,一旦发生误栓易出现严重并发症,因此在子宫肌瘤栓塞中该栓塞材料需谨慎选择。
Objective To evaluate clinical value of two embolic agents（mixed liquor of lipiodol and pingyangmycin, and polyvinyl alcohol）for uterine fibroids embolization. Materials and Methods 110 patients with uterine fibreids were divided into two groups .51 patients were embolized with mixed liquor of lipiodol and pingyangmycin（ goup A）. 59 patients were embolized with pol）vinyl alcohol （group B）. 110 cases had been following up 48 to 72months（average 36 ± 6months）, the clinical effects and complications were observed. Results The symptom of excessive menstrual blood volume was greatly improved in 48 out of 49 patients in group A, and 45 out of 45 patients in group B. The balked-related symptoms were improved in 13 out of 13 patients in group A, and 11 out of 11 patients in group B. There was no significant statistical difference in clinical effects between group A and B. The volume of uterus was reduced 50.92 ± 2.78% in group A and 51.87 ± 3.12% in group B. There was no significant statistical difference in the change of uterus＇volume between group A and B （t value 1.688, P 〉 0.005）. The volume of uterine fibroids was reduced 65.12 ± 5.68% in group A and 62.94 ± 7.23% in group B. There was no significant statistical difference in the change of fibroids＇ volume between group A and B （ t value 1.769, P 〉 0.05）. There was no significant statistical difference in serum sexual hormones level between group A and B. There was no significant statistical difference in incidences of slight complication between group A and B, but permanent ovarian failure was found in 3 cases of group A, non-targeted embolization of bladder was found in 1 cases of group A. The recurrent fibroids were found in 2 cases of group A and 2 cases of group B 2 years later after uterine fibroids embolization. Conclusion According to the middle and long term of uterine fibroids embolization, there is no significant difference in clinical effects and the incidences of complications between both embolic agents（ mixed liquor of lipiodol and pingyangmycim, pal）vinyl alcohol）. Due to the liquid character of lipiodol which is easy to cause serious complications as non-targeted embolization, the mixed liquor of lipiodol and pingyangmycin should be prudently chosen in uterine fibroid embolization.
出处
《临床放射学杂志》
CSCD
北大核心
2006年第4期361-365,共5页
Journal of Clinical Radiology
关键词
子宫肌瘤
栓塞
卵巢
功能
Uterus leiomyoma Embolization Ovary Function
