摘要
目的监测山东省消灭丝虫病后丝虫病的流行情况。方法系统阐述了1984～2002年丝虫病的监测结果。横向监测,采取病原学、媒介学、血清学、流动人口监测、晚期病人调查等方法。纵向监测,根据不同的地理方位及原丝虫病流行区发病率的高低,在全省各地共选择5个县5个乡(镇)18个行政村进行固定监测。结果横向监测,在全省74个流行县(市、区)共调查502个乡(镇)1345个自然村,血检954467人,检出微丝蚴阳性者30例,阳性率为0.003%;媒介调查,共解剖淡色库蚊378816只,检出阳性蚊虫161只,自然感染率为0.04%;血清学调查,间接免疫荧光法(IFA)检测10667人次,丝虫抗体阳性者148例,阳性率为1.39%,接近非流行区人群水平;流动人口监测,在45个县(市、区)335个乡4473个村庄共血检36559人,检出微丝蚴阳性者147例,阳性率为0.40%。纵向监测显示,累计检出微丝蚴阳性者59例,全部在3～6年内自然转阴,蚊媒自然感染率为0.04%,并呈逐年下降趋势。结论监测结果表明,各项指标均达到卫生部颁布的消灭丝虫病的标准。
Objective To investigate and supervise the prevalence of filariasis after its elimination in Shangdong province Methods From 1984 to 2002, Cross-sectional survey： survey of activity of permanent residents and mobile population, of mosquito vectors, of serum in human population, and of terminal patients were carried out. Longitudinal survey： according to different sites and the former incidence in these areas with the prevalence of filariasis, 5 towns and 5 countries and 18 administrative villages were chosen to be under a fixed surveillance. Results Cross-sectional survey, 502 towns and 1 345 villages were surveyed in 74 counties across the province, 30 microfilarial positives cases of 954 467 people were found, and the positive rate is 0.003 % ; During the survey of vectors, 378 816 Culex pipiens were dissected, 161 positive mosquitoes were detected, the infection rate is 0.04 % ; In the survey of serology, 10 667 cases were tested by indirect immunofluorescenee assay （ IFA）, those with positive filarial antibody were 148, the positive rate was 1.39 %, which was quite near to the level of that in non-prevalent areas; In the survey of mobile population, 36 559 people were tested in 4 473 villages of 355 towns of 45 county, 147 microfilarial positives were detected and the infection rate was 0.40 %. The longitudinal survey showed that 59 microfilarial positives are detected in total, and all turn negative automatically within 3-6 years. The average infection rate of mosquitoes was 0.04%, and reduced year by year. 3 066 cases were tested by IFA, and with the positives 108, the average positive rate is 3.52 %. Conclusion The results showed that all the indexes related to filariasis have come to the criterion of the elimination of filariasis issued by the ministry of health.
出处
《中国媒介生物学及控制杂志》
CAS
CSCD
北大核心
2006年第2期102-103,共2页
Chinese Journal of Vector Biology and Control
关键词
丝虫病
横向监测
纵向监测
Filariasis
Cross-sectlonal survey
Longitudinal survey
