摘要
测定60例脑卒中病人血浆皮质醇、甲状腺激素值,结果:(1)与正常组比较脑卒中组皮质醇、rT_3显著升高(P<0.01),T_3显著降低(P<0.01),出血组皮质醇、T_3变化尤为明显,而 T_4、TSH 无明显变化(P>0.05)。(2)皮质醇、甲状腺激素变化和病灶范围有密切关系。病灶越大,变化越显著。皮质醇值随出血量和梗塞面积的增加而升高,呈正相关。当出血量>30ml、梗塞面积>20cm^2时和 T_3、T_3/rT_3值呈负相关,与 rT_3值呈正相关。(3)出血量影响皮质醇生理节律:小量出血,生理节律存在;中量出血,生理节律消失;大量出血,生理节律逆转。(4)皮质醇、T_3/rT_3值可作为判断病情、估计预后的指标。
The levels of cortisol and thyroid hormones in 60 cases with stroke were de- termined.The results showed that:(1)The levels of cortisol and T_3,rT_3 were significant changes in stroke group.(2)The levels of cortisol had positive correlation with size of le- sions.The size of lesions had negative corrrelation with T_3 and T_3/T_4 but positive with rT_3 when the volume of hemorrhage was more than 30 ml or the area of infarction more than 20 cm^2.(3)The physiological rhythm of cortisol disappeared or reversed with increasing the volume of hemorrhage.(4)The levels of cortisol and T_3/T_4 may be a parameter to assess the severity and prognosis.
出处
《临床神经病学杂志》
CAS
1996年第1期6-8,共3页
Journal of Clinical Neurology
