摘要
目的观察艾司洛尔和尼卡地平用于心肌缺血患者在腹腔镜手术期间心电图S-T段改变的情况。方法90例心肌缺血患者随机分成A、B两组,在全麻下行腹腔镜手术,A组在全麻诱导气管插管后给予艾司洛尔40μg/(kg·min)和尼卡地平1μg/(kg·min)静脉泵注。B组为生理盐水对照。记录两组麻醉前、给药后30min、拔管前和拔管后心电图S-T段下移幅度。结果A组给药后30min、拔管前和拔管后S-T段下移幅度变小,较麻醉前有显著差异(P<0.05)。B组给药后30min、拔管前和拔管后S-T段下移幅度变大,较麻醉前有显著差异(P<0.05)。两组间给药后30minS-T段下移幅度有显著差异(P<0.05),拔管前和拔管后差异极显著(P<0.01)。结论艾司洛尔和尼卡地平用于心肌缺血患者能有效改善心肌供血。
Objective To observe the change in electrocardiogram S-T section of patients with myocardial ischemia received esmolol and nicardipine during laparoscopic surgery. Methods 90 patients with myocardial ischemia scheduled for laparoscopic surgery under general anesthesia were randomly divided into group A receiving esmolol 40 μg/（kg·min）and nicardipine 1μg/（kg·min）after endotracheal intubation and group B receiving normal saline as the control. Downward shift distance of electrocardiogram S-T section before anesthesia, at 30 minutes after administration, before and after extubation were recorded. Results In group A, the downward shift distance of S-T section was significantly decreased at 30 minutes after administration, before and after extubation compared with before administration（P〈0. 05）. The downward shift was significantly different between two groups at 30 minutes after administration（P〈0. 05）, before and after extubation （P〈0. 01）. Conclusion Esmolol and nicardipine are effective in improving blood supply to patients with myocardial ischemi.
出处
《华中医学杂志》
CAS
2006年第2期93-94,共2页
Central China Medical Journal
关键词
尼卡地平
艾司洛尔
心肌缺血
心电图
Nicardipine Esmolol＇ Myocardial Ischemia Electrocardiogram
