摘要
目的分析手术切除范围及放疗对预防神经节细胞胶质瘤术后复发的意义。方法回顾性分析28例经手术治疗神经节细胞胶质瘤的手术切除范围及放疗后病人肿瘤复发情况,随访7个月￣6年10个月。结果18例肿瘤全切病人中,2例复发,均未经放疗;6例近全切除的病例中2例复发,其中4例术后加行了放疗;4例大部切除的病例中3例复发,其中2例术后加行放疗。死亡1例,失访1例。结论手术治疗与神经节细胞胶质瘤术后是否复发关系最密切,全切能够明显减少肿瘤的复发,放疗不能有效地控制肿瘤复发,但对于分化较差的肿瘤可考虑加行放疗。
Objective To investigate the implication of the extent of resection and radiotherapy in preventing relapse of ganglioglioma after operation. Methods Twenty-eight patients who underwent resection of ganglioglioma were retrospective analyzed for the extent of resection and relapse of ganglioglioma after radiotherapy. The follow-up time was 7 months to 6 years and 10 months. Results Two cases without radiotherapy relapsed in the 18 patients who underwent total resection of the tumor; 2 cases relapsed in the 6 patients undergoing subtotal resection of the tumor, of whom 4 received radiotherapy; 3 cases relapsed in the 4 patients whose tumor was largely resected, of whom 2 received radiotherapy. One case died and 1 case lost follow-up. Conclusion Relapse ofganglioglioma after operation is closely related to the extent of resection and total resection of the tumor can decrease its relapse. Radiotherapy cannot effectively decrease its relapse, but should be used as an adjuvant therapy for poorly-differentiated tumors.
出处
《中国微侵袭神经外科杂志》
CAS
2006年第4期148-150,共3页
Chinese Journal of Minimally Invasive Neurosurgery
