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前列地尔治疗糖尿病周围神经病变疗效观察 被引量:6

Effects of Alprostadil on Diabetic Neuropathy
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摘要 目的探讨前列地尔治疗2型糖尿病合并周围神经病变的疗效。方法选择64例2型糖尿病合并周围神经病变患者,随机分为治疗组(加用前列地尔)和对照组(未加用前列地尔)。观察2组治疗前后症状改善、神经传导速度的情况。结果治疗组临床症状、运动神经传导速度(MNCV)、感觉神经传导速度(SNCV)较对照组均有明显好转(P<0.05)。结论前列地尔治疗糖尿病周围神经病变疗效较好,且有较高的安全性。 Objective To observe the effects of alprcstadil on patients with type Ⅱ diabetes mellitus (T2DM) complicated with peripheral neuropathy. Methods 64 T2DM patient complicated peripheral neuropathy were divided into therapy group (treated with alprostadil) and control group randomly (treated without alprostadil). The changes of symptom and motor nerve conduction velocity (MNCV), sensory nerve conduction velocity (SNCV) of each group before and after treatment were observed, Results The symptom MNCV and SNCV in therapy group were better than those of the control group ( P 〈 0.05 ). Conclusions Alprostadil is effective and safe on treating diabetic neuropathy.
作者 钟守国
出处 《实用全科医学》 2006年第3期353-354,共2页 Applied Journal Of General Practice
关键词 前列地尔 2型糖尿病 周围神经病变 Alprostadil T2DM Peripheral neuropathy
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