摘要
目的观察硫酸软骨素和氨基葡萄糖对小鼠免疫功能的影响。方法采用连续灌胃给药,30 d后取脾脏进行淋转功能和细胞活性测定,并取胸腺称重,计算胸腺指数。结果硫酸软骨素和氨基葡萄糖对小鼠T淋转功能和NK细胞活性有明显的促进作用(P<0.05),硫酸软骨素对小鼠胸腺指数有明显的提高作用(P<0.05)。结论表明硫酸软骨素和氨基葡萄糖均可明显提高机体的免疫功能。
Objective To observe effect of Chondroitin sulfate and D-glucosamine on immunological function in mice. Methods To take medicine consecutively by orally given for 30 days , respectively; then to measure activity of NK cell and transform function of T lymph cell, and weighed thymus glands, counted thymus glands index in mice spleen. Results It is showed that had all obvious enhance activity of NK cell and transform function of T lymph cell with Chondroitin sulfate and D-glucosamine, respectively （P〈0.05） ; but D-glucosamine had also increased thymus glands index（P〈0.05）. Conclusion It is suggested that Chondroitin sulfate or D-glucosamine could have reinforced immunological function in mice.
出处
《现代中药研究与实践》
CAS
2006年第2期36-38,共3页
Research and Practice on Chinese Medicines
关键词
硫酸软骨素
氨基葡萄糖
免疫功能
小鼠
Chondroitin sulfate
D-glucosamine
immunological function
mice
