摘要
对９１７例４０岁以上健康人利用６种方法同时进行糖尿病（ＤＭ）流行病学调查。按ＷＨＯ标准初筛出ＤＭ９４例，糖耐量异常（ＩＧＴ）９２例。方法①ＦＰＧ≥７．８ｍｍｏｌ／Ｌ；②ＦＰＧ≥６．７ｍｍｏｌ／Ｌ；③餐后２ｈ血糖≥１１．１ｍｍｏｌ／Ｌ；④空腹尿糖≥＋；⑤餐后２ｈ尿糖≥；⑥餐后２ｈ尿糖≥和（或）ＦＰＧ≥６．７ｍｍｏｌ／Ｌ并联阳性。结果①④法特异度高，灵敏度低，只查出ＤＭ１／３许。②⑤法灵敏度也低。③法灵敏度９８．１％，特异性１００％，但大规模健康普查时就要抽两次静脉血，难以做到。⑥法灵敏度８０．４％，特异性９４．０％，仅次于③法，操作与普查同步，可作为健康普查时早期诊断Ⅱ型ＤＭ初筛；即对普查时血尿化验不够ＤＭ标准而餐后２ｈ尿糖≥或ＦＰＧ≥６．７ｍｍｏｌ／Ｌ的可疑患者再进行餐后２ｈ血糖或ＯＧＴＴ确诊ＤＭ或ＩＧＴ，为大规模防治ＤＭ打下基础。
We have made epidemiological studies in 917 health check up subjects aged≥40 years to evaluate six different methods in sifting out diabetes mellitus(DM)and impaired glucose tolerance(IGT).Ninety four of 917 people met WHO criteria for DM and 92 for IGT.Six methods included fasting plasma glucose(FPG) level≥7.8mmol/l(method 1),FPG≥ 6.7 mmol/l(method 2),2h postload plasma goucose≥11.1mmol/l(method 3),fasting urinary glucose level≥(+)(method 4),2h postload urinary glucose≥ (+++) (method 5),and method 2 and/or method 5 positive(method 6).Method 3 had a specifictity of 100% and sensitivity of 98.1% for defining DM or IGT and method 6 a sensitivity of 80.4% and specificity of 94.0%.Other 4 methods had a high specificity but low sensitivity.Although method 3 had the highest specificity and sensitivity,it would increase the workload for the health check up in a great population that blood was drawn by venipucture twice for each person.Method 6 had a higher sensitivity and specificity and could be used to sift out suspects in health check up people for further oral glucose tolerance test or 2h postload plasma glucose level measurement.
出处
《实用老年医学》
CAS
1996年第4期175-176,共2页
Practical Geriatrics
关键词
糖尿病
糖耐量异常
流行病学
血糖
尿糖
Diabetes mellitus Impaired glucose tolerance Epifudemiology Plasma glucose Urinary glucose.
