摘要
目的 探讨前列腺素E1对糖尿病肢端坏疽的治疗效果。方法自2004年6月-2006年2月对58例患者，采取随机分组，治疗组30例用前列腺素E1加基础治疗方法，对照组28例用复方丹参加基础治疗，观察84d。结果治疗组溃疡总有效率90％，疼痛总有效率83％，观察组溃疡总有效率60％，疼痛总有效率57％，治疗前后两组患者的股动脉、腘动脉及足背动脉内径和血流量差异均有统计学意义（P〈0．05）。结论前列腺素E1是治疗糖尿病肢端坏疽的有效药物。
Objective To probe the effect of prostaglandin E1 （PGE1） in treating diabetic foot gangrene. Methods Fifty-eight patients were selected and divided into 2 groups randomly from Jun. 2004 to Feb. 2006. Then the 30 patients in the experimental group were treated with prostaglandin E1 adding basic therapy, while 28 patients in control group were treated with compound dansen for 84 days. Results In experimental group, the total curative rate of foot ulcer was 90% and the total curative rate of the pain was 83% ,while in control group the＇total curative rate of foot ulcer was 60% and the pain was 57%. There curative were significant differences（ P 〈 0.05） in inner diameter and the blood flow in the femoral artery,popliteal artery and dorsal pedal before and after treatment in two groups. Conclusion Prostaglandin E1 is an effective drug for treating diabetic foot gangrene.
出处
《中原医刊》
2006年第10期16-17,共2页
Central Plains Medical Journal
