摘要
研究了43例急性脑出血病人的巨噬细胞吞噬功能和T淋巴细胞亚群的变化规律。结果显示:病人组巨噬细胞吞噬率和吞噬指数普遍降低,与对照组比较差异显著(P<0.01);CD_4和CD_8明显增高(P<0.05),CD_4/CD_8明显降低(P<0.05)。提示急性脑出血病人免疫功能下降。将病人随机分为两组进行治疗,西药组应用20％甘露醇、速尿、脑活素治疗,中西药组除以上治疗外每日加服1剂大承气汤,1月后复查各项指标,结果显示:中西药组各项指标均较西药组好转,其中吞噬率、吞噬指数、CD_4/CD_8较西药组明显增高,CD_8较西药组明显降低(P<0.05),提示大承气汤对脑出血患者有明显的免疫调节功能。
The phagocytic' function of macrophages and changing* rules of T lymphocyte subgroups were examined in 43 cases of acute .cerebral hemorrhage. Results showed ttiat. there were general decrease of macrophage phagocytosis and phagocytic index. Comparison between these results arid that of the controlled group revealed significant difference (P<0. 01), CD4 and CD8 were also markedly increased (P < 0. 05); CD4/CD8 markedly lowered (P<0. 05), suggesting that there is a decrease of immune function in such patients. When the patients were randomly divided into 2 groups and treated by' 20% mannitol. furosemide, cerebratin in one group, and the other group treated by, in addition to the above remedies, Dachengqi Decoction 1 potion q. d. All indexes were re - examined 1 month later. Results showed that all indexes in the latter group were better than that the former. Among others, rate of phagocytosis, phagocytic indices, CD4/CD8 were markedly higher in the integrated medicine group CD8 markedly lowered (P<0. 05) in the integrated group, suggesting that Dachengqi Decoction yielded marked regulating action on immunity in acute cerebral hemorrhage cases.
出处
《中医杂志》
CSCD
北大核心
1996年第1期28-29,共2页
Journal of Traditional Chinese Medicine
关键词
脑出血
中医药疗法
大承气汤
免疫功能
Cerebral hemorrhage/TCM therapy Cere-bral hemorrhage/immunology Dachengqi Decoction/treatment
