摘要
[目的]探讨3-6岁中重度单纯性肥胖儿童血脂、血清铁蛋白与脂肪肝的关系。[方法]选取大连市托幼园所的在园儿童111例,中重度单纯性肥胖儿童69例,正常对照组42例。两组均进行血脂、血清铁蛋白及肝脏B超检查。[结果]①肥胖组血清总胆固醇、甘油三酯、低密度脂蛋白胆固醇、血清铁蛋白均高于正常对照组(P<0．01)。②肥胖组血清铁蛋白与甘油三酯具有相关性(r=0．324,P<0．05)。③B超检查显示肥胖组儿童有13例并发脂肪肝,发病率为18．84％;正常对照组无1例脂肪肝发生(P<0．01)。④肥胖脂肪肝组血清铁蛋白高于肥胖无脂肪肝组(P<0．05)。 [结论]中重度单纯性肥胖儿童已发生明显的脂代谢紊乱;中重度单纯性肥胖儿童并发脂肪肝较为常见,发病率为 18．84％;血清铁蛋白对中重度单纯性肥胖儿童脂肪肝的早期诊断可能具有重要意义。
[Objective] To study on the relationship between serum ferritin concentrations and fatty liver in the above medium simply obesity of 3-6 years old. [Methods] 111 children of 3-6 years old coming from kindergarten were collected（69 children of the above medium simply obesity and 42 children in control）. All children were examined by lipid, serum ferritin and uhrasonography of liver. [Results] ①The levels of serum total cholesterol, triglyceride, low-density lipoprotein cholesterol and serum ferritin in obesity were significantly higher than those in control（P〈0.01）. ②The relationship between the levels of serum ferritin and triglyceride was positive in obesity（r=0. 398, P〈0.05）. ③Uhrasonography of liver showed that there were 13 children with fatty liver in obesity, and there was no one with fatty liver in control, and the incidence of fatty liver in obesity was 18.84%. There was significant difference between two groups（P〈0.01）. ④The levels of serum ferritin with fatty liver were significantly higher than those without fatty liver in obesity（P〈S0.05）. [Conclusions] The disorder of lipid metabolism has already taken place in above medium simply obese children. Fatty liver is common in above medium simply obese children, and the incidence of which is 18. 84% The serum ferritin is an early way to diagnose fatty for simply obesity.
出处
《中国儿童保健杂志》
CAS
2006年第3期231-232,共2页
Chinese Journal of Child Health Care
基金
国家自然科学基金(30571577)
关键词
单纯性肥胖症
3~6岁儿童
铁蛋白
脂肪肝
simply obesity
346 years old children
serum ferritin
fatty liver
