摘要
用七味白术散治疗小儿轮状病毒肠炎６０例，止泻效果优于口服补液盐（ＯＲＳ）组（Ｐ＜０．０５），患儿大便中Ｎａ＋、糖浓度，轮状病毒抗原阳性例数均明显低于ＯＲＳ组。在动物实验中，七味白术散对ＮＩＨ小鼠新生幼仔实验性轮状病毒感染具有较好治疗作用，可降低小鼠病死率，并能降低鼠粪中Ｎａ＋、糖含量，促使轮状病毒抗原消失，减轻感染小鼠小肠粘膜的损伤和绒毛脱落。
Sixty cases of rotaviral enteritis treated with Qiwei Baizhu Powder(QWBZP) revealed a better efficacy than that treated with Oral Rehydration solution(ORS, X2=6.07,P<0.05). The content of Na+ and glucose as well as number of patients with positive human rotavirus(HRV) antigen in faeces in QWBZP group were less than that in ORS group (x2=18.09,P<0.05). In experimental study, QWBZP was found to be effective in treating HRV enteritis of newborn NIH mice in vivo,as compared with the control groups, the mortality of mice was decreased by 73.3%, the content of Na+ and glucose as well as number of mice with positive HRV antigen in faeces was markedly reduced, the pathological changes of intestine such as the damage of smalll intestinal mucosa and the exfoliation of intestinal villi were also obviously aileviated.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1996年第3期132-135,共4页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家自然科学基金
关键词
七味白术散
轮状病毒
病毒性肠炎
中医药疗法
Qiwei Baizhu Powder, pharmacodynamics, rotaviral enteritis, traditional Chinese medicine therapy
