摘要
血、尿α１－微球蛋白（α１－ＭＧ）及尿白蛋白（Ａｌｂ）联合检测可作为肾功能损害早期诊断的灵敏指标。对２２１例各类肾脏疾病患者和５７例正常人（对照组）的血和尿α１－ＭＧ、β２－微球蛋白（β２－ＭＧ）及尿Ａｌｂ进行了放免检测。结果表明：患者血和尿α１－ＭＧ、β２－ＭＧ及尿Ａｌｂ值均明显高于对照组（Ｐ＜０．００１和Ｐ＜０．０５）。患者阳性率：血和尿的α１－ＭＧ分别为８２．４％和８４．２％；血和尿的β２－ＭＧ分别为７９．６％和７３．３％；尿Ａｌｂ为９１．４％。显示了α１－ＭＧ、Ａｌｂ阳性率高于β２－ＭＧ，故在各种肾病早期诊断和恢复期观察应首选α１－ＭＧ和Ａｌｂ。
The combined determination of serum and urinary α 1 MG and urinary albumin (Alb) can be used as the sensitive indices of the early diagnosis of kidney function. The serum and urinary α 1 MG, β 2 MG and urinary Alb values for 221 cases with different kidney diseases and 57 normal subjects are measured by radioimmunoassay. The results show that the values of serum and urinary α 1 MG, β 2 MG and urinary Alb of patients are significantly higher than that of healthy subjects( P <0.001 and P <0.05) . The patients positive rates of serum and urinary α 1 MG is 82.4% and 84.2% respectively, serum and urinary β 2 MG is 79.6% and 73.3% respectively, and urinary Alb is 91.4%. It is suggested that the positive rates of serum and urinary α 1 MG and urinary Alb is higher than that of serum and urinary β 2 MG. So the determination of α 1 MG and Alb should be used in the early diagnosis and recovery observation of different kidney diseases.
出处
《同位素》
CAS
北大核心
1996年第2期102-105,共4页
Journal of Isotopes
