摘要
报道了在多聚磷酸作用下,在75℃下将苯并-18-冠-6用丙烯酸酰化环合,反应2h,合成了茚满酮-[1]-5,6-苯并- 18-冠-6(A),其收率为30％．后以乙醇为溶剂,以(A)和氨基脲为反应物,用醋酸和醋酸钠调节PH为3-4,在80℃左右反应 4h,合成了茚满酮-[1]-缩氨基脲-5,6-苯并-18-冠-6(B),其收率为56％．经由IR,MS和元素分析对合成的二种新物质的结构进行了鉴定．
Indanone-[ 1 ]-5,6-benzo-18-crown-6 （A） has been synthesized by acylation of benzo-18-crown-6 with crylic acid in polyphosphoric acid at 75 degree centigrade for 2h. The yield is 30%. Then alcohol is used as solvent, adjusted the pH value between 3 and 4 with acetic acid and sodium acetate. Indanone-[ 1 ] -5,6-benzo-18-crown-6（A） was reacted with semicarbazide at 80 degree centigrade for 4h, to give indanone-[ 1 ]-semicarbazone-5,6-benzo-18- crown-6, the yield was 56%. The structure of the two new products were characterized by elemental analysis, IR and mass spectrometry.
出处
《南京师范大学学报（工程技术版）》
CAS
2006年第2期54-56,共3页
Journal of Nanjing Normal University(Engineering and Technology Edition)
基金
陕西省教育厅自然科学基金资助项目(97K053).
关键词
冠醚
酰化
茚满酮
多聚磷酸(PPA)
crown ether, acylation, indanone, polypbosphoric acid （PPA）
