摘要
目的观察伴湿热证的2型糖尿病,经胰岛素强化血糖控制、并联合葛根芩连汤加味对湿热证候的疗效及胰岛素用量的影响。方法中药组以葛根芩连汤加味配合胰岛素强化治疗,常规组单予胰岛素强化治疗。结果中药组14例,显效5例,有效6例,无效3例,总有效率为78．6％;常规组16例,显效2例,有效7例,无效7例,总有效率56．3％;两组比较,差异有显著性(u=2．58,P<0．01)。经胰岛素强化治疗血糖达标时间(天)中药组(4．54±0．50)较常规组(5．31±0．57)短(P<0．01);治疗结束时胰岛素用量较血糖达标时中药组减少(9．07±6．51)U,常规组减少(4．38±5．94)U;两组比较,差异有显著性(P<0．05)。结论对伴湿热证的2型糖尿病,在短期胰岛素强化治疗基础上,联合葛根芩连汤加味治疗,可以相对减少胰岛素用量,并取得较好的临床疗效。
Objective To observe the effect of Gegen Qinlian Decoction （GQD） in combination with shortterm intensive insulin treatment on type 2 diabetes mellitus （T2DM） of dampness-heat syndrome and its influence on dosage of insulin used. Methods The GQD group （ n = 14） was treated by GQD and insulin, while the conventional group （n = 16） was given insulin intensive treatment alone. Results In the GQD group, the treatment was markedly effective in 5 patients, effective in 6 and ineffective in 3, the total effective rate being 78.696, much better than that in the conventional group （2,7,7 and 56.3% respectively, u = 2.58, P 〈 0.01 ）. And it took less time for controlling blood glucose （BG） in the GQD group （4.54 ± 0.50 days） than that in the conventional group （5.31 ± 0.57 days, P〈0.01） ; Furthermore, by the end of the treatment course, as compared with that at the time just after BG being controlled, the daily average insulin dosage used in the GQD group reduced by 9.07 ± 6.51 U, while it was only 4.38 ± 5.94 U in the conventional group, showing significant difference between them （P 〈 0.05）. Conclusion Based on short-term insulin intensive treatment, the combined using of GQD could reduce the dosage of insulin used and shows better clinical curative effect for patients with T2DM of dampness-heat syndrome.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2006年第6期514-516,520,共4页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
2型糖尿病
湿热证
胰岛素强化治疗
葛根芩连汤
type 2 diabetes mellitus
dampness-heat syndrome
insulin intensive treatment
Gegen Qinlian Decoction
