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survivin在胃癌组织中的表达及意义 被引量：3

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摘要 目的探讨胃癌组织中凋亡抑制因子survivin的表达及其与临床病理参数的关系,评价survivin的表达在胃癌预后判断中的价值。方法应用免疫组织化学SP方法,检测60例胃癌、7例正常胃组织中survivin的表达。结果survivin在7例正常胃标本中均为阴性;60例胃癌组织中34例阳性,阳性率56·7%。其表达状态与胃癌的分化程度、淋巴结转移有关;与TNM分期有关,但统计学上无明显差异;与患者年龄、性别、肿瘤大小无明显相关性。结论survivin在胃癌的发生、发展中起重要作用,检测胃癌组织中survivin的表达可作为评价胃癌生物学行为和判断预后的重要指标。
作者 王彩芹 姜维华
机构地区 北华大学附属医院病理科 北华大学
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第6期771-772,共2页 Chinese Journal of Gerontology
关键词 SURVIVIN 免疫组织化学 胃癌
分类号 R735.2 [医药卫生—肿瘤]
  • 相关文献

参考文献6

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二级参考文献16

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共引文献44

同被引文献29

  • 1李侠,王玲,张霞,李玉,许复郁.老年非小细胞肺癌生存素基因表达与微血管密度[J].中国老年学杂志,2005,25(2):136-138. 被引量：3
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引证文献3

二级引证文献6

中国老年学杂志
2006年 第6期

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