摘要
目的通过对收集到的药品不良反应信息的汇总分析,发挥药品不良反应监测工作的指导作用,以保障公众用药安全。方法采用病例回顾性研究方法,对哈尔滨市2004年4月～2005年12月收集到的515例药品不良反应病例报告进行综合分析。结果药品不良反应报告主要来源于医疗机构,占97.86%;新的不良反应占24.86%,严重的不良反应占6.99%;不良反应主要累及系统-器官为皮肤及其附件;抗微生物药品品种占43.96%,不良反应例数占63.3%;给药途径以静脉用药为主,占84.66%。结论切实加强药品不良反应监测工作,提高报告质量和分析评价能力,为维护公众健康服务。
Objective By analyzing ADR reports received in Harbin provice, to promote instructional function of ADR monitoring to ensure safe use of medicine in Public. Method 515 ADR reports received between April 2004 and December 2005 in Harbin were comprehensively analyzed using retrospective case study. Result The ADR reports are mainly from hospitals, account for 97.86%. The new ADR reports are account for 24.86%, and serious for 6.99%. Adverse reactions are mainly skin reactions. The antimicrobial drugs are the most drugs associated with ADR, account for 43.96%; the number of ADR reports are account for 63.3%. The main route of administration is injected in vein, account for 84.66%. Conclusion Through strengthening ADR monitoring, quality of reports and ability of evaluation need to be improved to protect public health.
出处
《中国药物警戒》
2006年第4期207-209,240,共4页
Chinese Journal of Pharmacovigilance
