摘要
目的:观察睡眠状态下阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者上气道扩张肌肌电活性的变化,探讨其在OSAHS中的作用及意义。方法:对中、重度OSAHS患者69例(OSAHS组)及健康志愿者20例(对照组)于诱导睡眠后分别行颏舌肌、腭帆张肌和腭帆提肌等上气道扩张肌肌电图的检测并与诱导睡眠前比较。结果:①清醒状态下OSAHS组上气道扩张肌肌电水平较对照组高(均P<0.01);②与清醒状态比较,睡眠状态下OSAHS组上气道扩张肌肌电水平显著下降(均P<0.01);③从清醒状态到睡眠状态,OSAHS组上气道扩张肌肌电水平下降幅度明显大于对照组(均P<0.01)。结论:OSAHS患者清醒状态下上气道扩张肌肌电活性代偿性升高及睡眠状态下失代偿是该病发生的重要病理生理机制。
Objective：To observe the changes of the eleetromyography（EMG） of the dilatation muscles of upper airway in patients with obstructive sleep apnea-hyponea syndrome （OSAHS） under asleep condition and to explore their functions and significance. Method：The myoelectronic activity of levator palatini muscle, tensor palatini muscle ,genioglosus muscle was measured by ENG in patients with moderate to serious OSAHS before and after induction of sleep and was compared with normal control. Result：（1）The myoelectronic activity of dilation muscles of the upper airway in OSAHS patients were higher than that in control under awake condition（ P〈0.01）. （2） When the patients were asleep, the myoelectronic activity of these muscles dropped significantly（ P 〈0.01）. （3） The decrease of myoelectronic activity of dilatation muscles of upper airway was more dramatic in patients with OSAHS than that in control when turned from awake condition to asleep condition（ P〈0.01）. Conclusion： The compensative raise of myoelectronic activity of dilatation muscles of upper airway under awake condition and the decompensation when asleep in patients with OSAHS were important in the pathogenesis.
出处
《临床耳鼻咽喉科杂志》
CSCD
北大核心
2006年第14期642-644,共3页
Journal of Clinical Otorhinolaryngology
