摘要
目的:探讨原发性肝癌(PHC)患者乙肝病毒感染与血清甲胎蛋白(AFP)的关系。方法:应用EL ISA及放射免疫技术分别测定135例PHC患者HBV-M及AFP。结果:PHC患者感染模式分析中,HBV感染121例(89.6%),感染模式HB sA g、HB eA b、HB cA b 3项阳性(小三阳)为68例(50.4%)。135例PHC患者中,HBV-M阳性者AFP升高比例明显高于HBV-M阴性者(P<0.01)。结论:HBV是原发性肝癌发生的重要病因,在PHC患者中AFP升高与HBV感染有关。
Objective： To study the relationship between HBV and AFP in primary hepatic carcinoma （PHC）. Methods： The antigen systems （HBV-M） and AFP were detected in 135 cases of PHC with the method of ELISA. Results： The model of HBV infection in patients of PHC analysis showed that 121 cases were infected by HBV （89.6%）. 68 cases showed ＂Secondary 3 positive＂ （HBsAg, HBeAb, HBcAb）in the infective model （50.4%）. In the total 135 patients with PHC, the increase rate of AFP in the group with positive HBV-M were obviously higher than that in the negative group （P〈0.01）. Conclusions： HBV is an important pathogeny to PHC in which the increase of AFP has a close relationship to HBV infection.
出处
《华夏医学》
CAS
2006年第3期394-395,共2页
Acta Medicinae Sinica
