摘要
目的观察青光眼滤过术中应用丝裂霉素c（MMC）的效果。方法对36例42眼青光眼患者行小梁切除术。术中应用0．4g·L^-1。MMC，时间为4min，观察术后并发症的发生、滤过泡的形成以及术后1月、3月、6月的眼压变化情况。结果（1）并发症：术后早期出现低眼压性浅前房（眼压≤5mmHg）4眼，薄壁滤过泡5眼，滤过泡渗漏2眼；角膜上皮点状或弥漫缺损3眼，均在3～7d内自行恢复；术后前房有少量出血者2例，3d内自行吸收。（2）滤过泡：Ⅰ、Ⅱ型滤过泡36眼；Ⅲ型滤过泡4眼；Ⅳ型滤过泡2眼。（3）眼压：术后1月42眼、术后3月38眼、术后6月34眼眼压均在10～20mmHg（1kPa=7．5mmHg）。需用一种降眼压滴眼液可控制在20mmHg以下有6眼，眼压控制不良再手术有2眼。结论青光眼小梁切除术后由于MMC应用不当而发生的并发症及其他不良后果仍不容忽视。
Objective To observe the effects of application of MMC in the glamcoma drainage surgery. Methods 0.4 g· L^-1 MMC was applied on 42 eyes of 36 cases in glaucoma trabeculectomy operation for 4 minutes. The syndrome after the operation, the formation of drainage bleb and variation of operation in the first month, the third month, and the sixth month were observed respectively. Results （ 1 ） Syndrome： in the early period of operation, low pressure of shallow anterior chamber in 4 eyes （eye pressure lower than 5 mrnHg）, thin skin drainage bleb in 5 eyes, leakage of drainage bleb were occurred in two eyes; spot or extensive damage on the upper-skin of cornea appeared in 3 eyes, which recovered automatically in 3 to 7 days; bleeding in front antrum appeared in 2 cases, blood was absorbed in 3 days. （2） Drainage bleb：Model Ⅰ and Ⅱ was 36 eyes;Model Ⅲ was 4 eyes; Model Ⅳ was 2 eyes. （3） Eye pressure：42 eyes in 1 month postoperatively 38 eyes in 3 month;34 eyes in 6 month remained 10-20 mmHg.6 eyes were controlled by eye-pressure-drop, 2 eyes were improperly controlled on eye-pressure and re-operation was carried out.Conclusion It is very noticeable to reduce the syndrome and other kickback after the glaucoma trabeculectomy operation.
出处
《眼科新进展》
CAS
2006年第8期624-625,共2页
Recent Advances in Ophthalmology
