摘要
心脑血管血栓性疾病是一种常见疾病,抗血小板药物可以有效预防和治疗血栓性疾病,氯吡格雷是一种新型的具有不可逆抑制血小板聚集的噻吩并吡啶化合物。本文简要综述氯吡格雷的一些合成方法,并进行对比分析和简单评价。
Cardiac and cerebrovascular disease is a common disease. It is well recognized that antiplatelet agent is effective in the prevention and treatment of thrombosis. Clopidogrel is one of thieno pyridine derivatives, which can inhibit ADP-induced platelet aggregation. The progress of synthesis research work of clopidogrel is briefly reviewed, compared and evaluated in this article.
出处
《安徽医药》
CAS
2006年第8期614-616,共3页
Anhui Medical and Pharmaceutical Journal
