摘要
戊型肝炎病毒(HEV)是一种RNA病毒,引起一种急性传染性肝炎—戊型肝炎(HE),戊型肝炎主要经粪—口途径传播,通常是由于饮用被HEV污染的水而引起。其中,在亚洲、非洲和美洲等发展中国家人群中发生比较普遍,在一些地区可占到急性病毒性肝炎的50%,是导致发病和病死的重要因素。中国是戊肝高流行区,发病数、发病率均呈现连续快速增长的态势。人类对HEV普遍易感,在孕妇中可导致流产或死亡,病死率高达到20%￣30%,易感人群以大龄儿童和青壮年为主,幼儿少见。HEV不仅可以侵犯人类,而且可以在动物中广泛分布和传播,戊型肝炎是一种人畜共患性传染病。在此,从病原学、流行病学、检测方法及其疫苗的研制几个方面对其进行了综述。
Hepatitis E virus （HEV） is one kind of RNA virus, which mainly causes one kind of acute infectious hepatitis-hepatitis E. Hepatitis E is transmitted in a faecal-oral route, and usually is caused by contaminated drinking water. Hepatitis E occurs predominantly in developing countries, in Asia, Africa and America. Hepatitis E accounts for more than 50% of acute viral hepatitis in some areas, and is important agent which causes illness and to die. Our country is HE highly prevalent area; the disease incidence rate presents the fast growth. Human is prone to infect HEY, which cause the miscarriage or the death in pregnant woman, and mortality rate reaches 20%-30%. The infection crowd primarily is the great age child and the young adults, while the baby is rare. HEV may infect not only the human, but also is widespread in the animal. This article has carried on the summary of it from the etiology, the epidemiology, the examination method and its vaccine development several aspects.
出处
《中国农学通报》
CSCD
2006年第8期26-29,共4页
Chinese Agricultural Science Bulletin
基金
石河子大学地方与民族高发病省部共建实验室开放基金"新疆地区羊戊型肝炎血清学流行病学调查"(2004-2)。
