摘要
目的观察米非司酮配伍米索前列醇用于妊娠10～16周早中孕引产的效果。方法对46例妊娠10～16周,自愿要求终止妊娠的健康妇女作为研究组,对研究组采用米非司酮配伍米索前列醇方法引产,胎儿自然排除后即行清宫术；选用同期同样条件46例宫颈插管后行钳刮术为对照组,对两组人工流产痛、术中情况进行统计学比较。结果研究组引产成功率为96%,其疼痛较对照组轻微减轻(P＜0．05)；术中情况有显著性差异P＜0．05。结论米非司酮配伍米索前列醇有胃肠道反应轻,手术时间短、出血少、疼痛轻、组织残留率降低,并发症少、成功率高等特点,是一种简便、有效、安全的终止早中妊娠的方法,值得临床推广应用。
Objective To observe the effects of combination of mifepristone plus misoprotol for induced abortion of 10 ～ 16 weeks of gestation. Methods Forty-six healthy pregnant women with 10-16 weeks of gestation who voluntarily requested to terminate the pregnancy were as study group. The pregnant women in study group were administered mifepristone plus misoprotol for termination of the pregnancy with removal of the uterine contents after natural expulsion of the fetus. The other 46 pregnant women with the same weeks of gestation and similar conditions were as control group. The pregnant women in the control group received dilatation of cervix and uterine curettage. The pain perception and information in the induced abortion were compared statistically. Results The successful abortion rate in the study group was 96% and pain perception of pregnant women in the study group in induced abortion was more slight （ P 〈 0.05 ）. The difference between the two groups in conditions of pregnant women during operation were significant （ P 〈 0. 05 ）. Conclusion Combination of mifepristone plus misoprotol for termination of pregnancy has many advantages, such as less side effects, short operation time, less hemorrhage, slight pain, reduced tissues residual rate, few complications and high successful rate. Mifepristone plus misoprotol for termination of the early or middle pregnancy is a simple, effective and safe method and is worthy to be popularized in clinic.
出处
《中国妇幼健康研究》
2006年第4期288-289,共2页
Chinese Journal of Woman and Child Health Research
关键词
米非司酮
米索前列醇
早中孕
引产
mifepristone
misoprotol
the first and the second trimester of pregnancy
induced abortion
