摘要
采用反相乳液法合成了载药淀粉微球,表征了微球的形貌和结构特征,研究了工艺条件改变对微球吸附量的影响规律。扫描电镜图片表明,淀粉微球呈圆球形,表面粗糙,孔隙发育。红外光谱图存在酰胺基吸收峰,说明可溶性淀粉与N,N′—亚甲基双丙烯酰胺发生了交联反应。引发剂用量、交联剂用量、反应温度、反应时间等因素的改变对微球吸附量有显著的影响。
The drug-carried starch microspheres were synthesized in reversed phrase emulsion system. We also focused on the morphologies,structure characteristics and influences of synthesis conditions on adsorption quantity of starch microspheres.The photos of SEM indicate that the starch microspheres are spherical particulates with rough surface and inherent pores.The adsorption peaks of amide group existed in infrared spectrogram proved that the soluble starch had crosslinked with N,N＇-methylene-bis-acrylamide.It had been confirmed that some parameters influenced odviously the adsorption performance of starch microspheres, which included dosage of initiator, dosage of crosslinking agent, reaction temperature and reaction time.
出处
《咸阳师范学院学报》
2006年第4期33-35,共3页
Journal of Xianyang Normal University
基金
陕西省教育厅产业化培育项目(02JC05)
国家自然科学基金项目(50573046)
关键词
淀粉微球
反相乳液法
载药
合成
吸附性能
starch microsphere
reversed phrase emulsion system
drug-carded
synthesis
adsorption performance
