摘要
目的探讨葛根素注射液治疗慢性充血性心力衰竭的近期疗效与安全性。方法将住院的慢性充血性心力衰竭患者随机分为葛根素治疗组和对照组,疗程10天,治疗前后记录6分钟步行距离,超声心动图检测左室功能参数。结果葛根素治疗组总有效率92.58%优于对照组79.62%(P<0.05),6分钟步行距离明显优于对照组(P<0.01),且未见不良反应。结论葛根素注射液治疗慢性充血性心力衰竭安全有效。
Objective To investigate the safety and the short-term outcome of intravenous puerarin in patients with chronic heart failure. Methods The patients with chronic heart failure were enrolled. The patients in puerarin group were treated with routine treatment and puerarin, while the patients in control group were treated without intravenous puerarin. The function of left ventricular was measured with echocardiography and six minutes walk test was performed at baseline and after 10 days follow-up. Results The rate of therapy effective of puerarin group is significantly higher than control group (92.58% vs. 79.62%, P〈0.05). The six minutes walking distance significantly increased in puerarin group than in control group (P〈0.01). No severe side effect was recorded during follow-up. Conclusions The treatment with puerarin for chronic heart failure is safe and effective.
出处
《海南医学》
CAS
2006年第10期27-27,155,共2页
Hainan Medical Journal