摘要
目的:应用磁共振扩散加权成像技术评价肝脏肿瘤介入手术疗效。方法:临床影像学诊断肝癌并行介入化疗栓塞术患者6例,VX2肿瘤造模新西兰大白兔2只。所有受检者及实验兔均先行常规T1W I、T2W I扫描,然后受检者在屏气下、实验兔在麻醉下进行2个不同扩散敏感因子b值的DW I扫描。结果:扩散扫描取不同b值时,介入手术术后与术前病灶表观扩散系数(ADC)的比值在110%以上时预后较好,低于110%时预后较差;病灶ADC值与肝脏ADC值的比值术后为术前的110%以上时预后较好,低于110%时预后较差。结论:磁共振扩散加权成像技术对评价肝脏肿瘤介入手术疗效似有指导价值。
Objective To evaluate the curative effect of chemoembolization of liver tumors by using of diffusionweighted imaging （DWI） magnetic resonance （MR）. Method 6 clinic liver tumor patients and 2 rabbits with VX2 tumor in liver first underwent routine T1-weighted and T2-weighted imaging of the whole liver, and then underwent DWI by using of 2 different b factors under breath-hold or general anaesthesia. Results By using of different b factors, chemoembolization postoperative apparent diffusion coefficient （ADC）focus/preoperative ADCfocus ≥ 110% , the prognosis was better, while the value 〈 110%, the prognosis was worse; postoperative ADCfocus/ADCliver preoperative ADCfocus/ADCliver ≥ 110%,the prognosis was better, while the value 〈 110%, the prognosis was worse. Conclusion It seems that DWI and ADC value can evaluate the curative effect after chemoembolization of liver tumors.
出处
《东南大学学报（医学版）》
CAS
2006年第5期357-361,共5页
Journal of Southeast University(Medical Science Edition)
关键词
磁共振成像
扩散加权成像
量化研究
栓塞
治疗性
肝癌
magnetic resonance imaging
diffusion-weighted imaging
quantitative study
emblization, therapeutic
liver cancer
